Papers - SHIRASUNA Koumei
-
Elevated S100A9 in preeclampsia induces soluble endoglin and IL-1b secretion and hypertension via the NLRP3 inflammasome. Reviewed
Ozeki A, Oogaki Y, Henmi Y, Karasawa T, Takahashi M, Takahashi H, Ohkuchi A, Shirasuna K
J Hypertens 40 84 - 93 2022
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
-
β-hydroxybutyrate suppresses NLRP3 inflammasome-mediated placental inflammation and lipopolysaccharide-induced fetal absorption. Reviewed
Hirata Y, Shimazaki S, Suzuki S, Henmi Y, Komiyama H, Kuwayama T, Iwata H, Karasawa T, Takahashi M, Takahashi H, Shirasuna K
J Reproductive Immunology 148 103433 2022
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
-
NLRP3 inflammasome is involved in testicular inflammation induced by lipopolysaccharide in mice. Reviewed
Sano M, Komiyama H, Shinoda R, Ozawa R, Watanabe H, Karasawa T, Takahashi M, Torii Y, Iwata H, Kuwayama T, Shirasuna K
American Journal of Reproductive Immunology 87 e13527 2022
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
-
IL1B triggers inflammatory cytokine production in bovine oviduct epithelial cells and induces neutrophil accumulation via CCL2. Reviewed
Nakamura Y, Aihara R, Iwata H, Kuwayama T, Shirasuna K
American Journal of Reproductive Immunology 85 ( 5 ) e13365 2021
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
-
Metabolomic profiles of plasma and uterine luminal fluids from healthy and repeat breeder Holstein cows. Reviewed
Funeshima N, Miura R, Katoh T, Yaginuma H, Kitou T, Yoshimura I, Konda K, Hamano S, Shirasuna K
BMC Veterinary Research 17 ( 54 ) 2021
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
-
Advanced maternal age induces fetal growth restriction with a decrease in placental inflammatory cytokines and immune cell accumulation in mice. Reviewed
Hirata Y, Katsukura Y, Henmi Y, Ozawa R, Shimazaki S, Kurosawa A, Karasawa T, Takahashi M, Ohkuchi A, Takahashi H, Kurosawa A, Torii Y, Takahashi H, Iwata H, Kuwayama T, Shirasuna K
J Reprod Dev 67 257 - 264 2021
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
-
Uncaria tomentosa extract (AC-11) improves pregnancy hypertension together with suppression of sFlt-1 and sEng. Reviewed
Oogaki Y, Ozawa R, Seshima K, Shinoda R, Torii Y, Takahashi H, Iwata H, Kuwayama T, Shirasuna K
Pregnancy Hypertens 26 127 - 132 2021
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
-
Role of the NLRP3 inflammasome in Preeclampsia Reviewed
Shirasuna K, Karasawa T, Takahashi M
Frontiers in Endocrinology 2020
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
-
Palmitic adic activates NLRP3 inflammasome and induces placental inflammation during pregnancy in mice Reviewed
Sano M, Shimazaki S, Kaneko Y, Karasawa T, Takahashi M, Ohkuchi A, Takahashi H, Kurosawa A, Torii Y, Iwata H, Kuwayama T, Shirasuna K*
Journal of Reproduction and Development 2020
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
-
Adverse reproductive effects of S100A9 on bovine sperm and early embryonic development in vitro Reviewed
Funeshima N, Tanikawa N, Yaginuma H, Watanabe H, Iwata H, Kuwayama T, Hamano S, Shirasuna K*
PLoS One 2020
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
-
Preeclamptic patient-derived circulating cell-free DNA activates the production of inflammatory cytokines via toll-like receptor 9 signaling in the human placenta Reviewed
Ozeki A, Tani K, Takahashi H, Suzuki H, Nagayama S, Hirashima C, Takahashi H, Iwata H, Kuwayama T, Ohkuchi A, Shirasuna K*
Journal of Hypertension 37 2452 - 2460 2019
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
-
The transfer of parthenogenetic embryos following artificial insemination in cows can enhance pregnancy recognition via the secretion of interferon tau Reviewed
Funeshima N, Noguchi T, Onizawa Y, Yaginuma H, Miyamura M, Tsuchiya H, Iwata H, Kuwayama T, Hamano S, Shirasuna K*
Journal of Reproduction and Development 65 443 - 450 2019
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
-
S100A8, which increases with age, induces cellular senescence-like changes in bovine oviduct epithelial cells Reviewed
Nakamura Y, Iwata H, Kuwayama T, Shirasuna K*
American Journal of Reproductive Immunology 2019
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
-
Olive leaf extract (OleaVita) suppresses inflammatory cytokine production and NLRP3 inflammasomes in human placenta Reviewed
Kaneko Y, Sano M, Seno K, Oogaki Y, Takahashi H, Ohkuchi A, Yokozawa M, Yamauchi K, Iwata H, Kuwayama T, Shirasuna K*
Neutrients 2019
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
-
Improvement of fertility in repeat breeder dairy cattle by embryo transfer following artificial insemination: possibility of interferon tau replenishment effect Reviewed
Yaginuma H, Funeshima N, Tanikawa N, Miyamura M, Tsuchiya H, Noguchi T, Iwata H, Kuwayama T, Shirasuna K*, Hamano S*
Journal of Reproduction and Development 65 223 - 229 2019
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
-
Age-related changes in the bovine corpus luteum function and progesterone secretion Reviewed
Hori K, Matsuyama S, Nakamura S, Iwata H, Kuwayama T, Miyamoto A, Shirasuna K*
Reproduction in Domestic Animals 54 23 - 30 2019
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
-
Exogenous nanoparticles and endogenous crystalline molecules as danger signals for the NLRP3 inflammasomes. Reviewed
Shirasuna K, Karasawa T, Takahashi M
Journal of Cellular Physiology In press 2018.11
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
-
Aggregation of human trophoblast cells into three-dimensional culture system enhances anti-inflammatory characteristics through cytoskeleton regulation. Reviewed
Seno K, Munakata Y, Sano M, Kawahara-Miki R, Takahashi H, Ohkuchi A, Iwata H, Kuwayama T, Shirasuna K
Int J Mol Sci 19 E2322 2018.09
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
-
Oxygen concentration modulates cellular senescence and autophagy in human trophoblast cells. Reviewed
Seno K, Tanikawa N, Takahashi H, Ohkuchi A, Suzuki H, Matsubara S, Iwata H, Kuwayama T, Shirasuna K
Am J Reprod Immunol In press 2018
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
-
Markedly higher sFlt-1/PlGF ratio in a woman with acute fatty liver of pregnancy compared with HELLP syndrome. Reviewed
Suzuki H, Nagayama S, Hirashima C, Takahashi K, Ogoyama M, Nagayama M, Shirasuna K, Matsubara S, Ohkuchi A
J Obstet Gynaecol Res In press 2018
Language：English Publishing type：Research paper (scientific journal)