Updated on 2024/07/12

写真a

TAMURA TOMOKO

Associate Professor

Title

Associate Professor

Laboratory Address

東京都世田谷区桜丘1-1-1 サイエンスポートS527

External Link

Studying abroad experiences 【 display / non-display

  • 2020.09 - 2021.09   カリフォルニア大学デイビス校   依命

Degree 【 display / non-display

  • 博士(農学) ( 2007.03 )

Employment Record in Research 【 display / non-display

  • Tokyo University of Agriculture   Faculty of Applied Bio-Science   Department of Nutritional Science   Assistant Professor

    2009.10 - 2014.03

  • Tokyo University of Agriculture   Faculty of Applied Bio-Science   Department of Nutritional Science and Food Safety   Associate Professor

    2014.04

Professional Memberships 【 display / non-display

  • 日本食品化学学会

    2018.04

Papers 【 display / non-display

  • Acute ultraviolet B irradiation increases cholesterol and decreases Cyp7a1 expression in the liver of female mice Reviewed International journal

    Takumi Yamane, Takahiro Okumoto, Tomoko Tamura, Yuichi Oishi

    Lipids   2024.07

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    Language:English   Publishing type:Research paper (scientific journal)  

    Recent studies have demonstrated that ultraviolet B (UVB) irradiation impacts both skin and hepatic functions. In this study, we investigated the effects of UVB irradiation on cholesterol metabolism in the liver. Hairless mice were exposed to UVB (1.6 J/cm2) irradiation. Dorsal skin and liver samples were collected 24 h after exposure. Total RNA was extracted from the skin and liver tissues, and used for DNA microarray analysis and real-time polymerase chain reaction (PCR). Hepatic mRNA expression of Cyp7a1 revealed a 4.4-fold decrease in the UVB (+) group compared to that in the UVB (-) group. No differences were observed in the expression of the other genes related to cholesterol metabolism. Additionally, the level of hepatic total cholesterol in the UVB (+) group was significantly higher than in the UVB (-) group. These findings suggest that acute UVB irradiation increases total cholesterol levels and decreases Cyp7a1 expression in the liver.

    DOI: 10.1002/lipd.12407

  • Genes related to cell wall metabolisms are targeted by miRNAs in immature tomato fruits under drought stress Reviewed International journal

    Hiroko Asakura, Mayui Tanaka, Tomoko Tamura, Yoshikazu Saito, Takashi Yamakawa, Keiko Abe, Tomiko Asakura

    87 ( 3 )   290 - 302   2022.12

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    Language:English  

    The metabolism of tomato fruits changes when plants experience drought stress. In this study, we investigated changes in microRNA (miRNA) abundance and detected 32 miRNAs whose expression changes in fruit. The candidate target genes for each miRNA were predicted from the differentially expressed genes identified by transcriptome analysis at the same fruit maturation stage. The predicted targeted genes were related to cell wall metabolisms, response to pathogens, and plant hormones. Among these, we focused on cell wall metabolism-related genes and performed a dual luciferase assay to assess the targeting of their mRNAs by their predicted miRNA. As a result, sly-miR10532 and sly-miR7981e suppress the expression of mRNAs of galacturonosyltransferase-10 like encoding the main enzyme of pectin biosynthesis, while sly-miR171b-5p targets β-1,3-glucosidase mRNAs involved in glucan degradation. These results will allow the systematic characterization of miRNA and their target genes in the tomato fruit under drought stress conditions.

    DOI: https://doi.org/10.1093/bbb/zbac209

  • Transcriptomic and Metabolomic Analyses Provide Insights into the Upregulation of Fatty Acid and Phospholipid Metabolism in Tomato Fruit under Drought Stress Reviewed

    Hiroko Asakura, Takashi Yamakawa, Tomoko Tamura, Reiko Ueda, Shu Taira, Yoshikazu Saito, Keiko Abe, and Tomiko Asakura

    J. Agric. Food Chem   69 ( 9 )   2894 - 2905   2021.02

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.jafc.0c06168

  • Yeast‐based reporter assay system for identifying the requirements of intramembrane proteolysis by signal peptide peptidase of Arabidopsis thaliana Reviewed

    Kenta Kusunoki Masako Hoshi Tomoko Tamura Tatsuya Maeda Keiko Abe Tomiko Asakura

    FEBS Openbio   10   1833 - 1842   2020.07

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: doi:10.1002/2211-5463.12936

  • Gene expression profiling in short-term imbibition of wheat: tools for dissecting of pasting properties of imbibed wheat Seeds. Reviewed

    Tomoko Tamura, Sayuri Akuzawa and Kiyoshi Mura

    Journal of Food Science   84   2019

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/1750-3841.14471

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Books and Other Publications 【 display / non-display

  • バイオサイエンスのための基礎化学

    ( Role: Joint author)

    化学同人  2023.03 

  • バイオサイエンスのための基礎化学

    平 修 , 杉浦 悠毅, 田村 倫子, 永井 俊匡

    化学同人  2023  ( ISBN:9784759821604

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    Language:Japanese  

    CiNii Books

  • 食べ物と健康―食品学

    大石祐一・服部一夫 (編集) ( Role: Joint author)

    光生館  2013 

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    Language:Japanese   Book type:Textbook, survey, introduction

    管理栄養士国家試験対策の参考書として、また、食品学総論を学習する教科書としてまとめた。ある食品の機能について、食品の中に存在するどのような成分がどのようなメカニズムで作用するのかまで学習できるよう、図表を多く用いて解説した。日本人の食事摂取基準および日本食品標準成分表に基づき作成した。
    総225ページ、第5章 食品の機能成分(pp.201-218) を担当

  • 食べ物と健康 (食物と栄養学基礎シリーズ4)

    吉田 勉 (監修), 佐藤 隆一郎, 加藤 久典 (編集)( Role: Joint author)

    学文社  2012 

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    Language:Japanese   Book type:Textbook, survey, introduction

    動物性、植物性食品を具体的に列挙し解説するとともに、食品の3つの機能、すなわち栄養成分としての機能、味覚・おいしさなどの機能、健康を維持し疾病にかかりにくくする機能を解説した。また、食に関わる法律や流通、食を取りまく環境問題においても具体例を挙げて解説した。管理栄養士の食品と健康における分野の国家試験対策となる一冊である。
    総245ページ、3 食品の機能(pp.91-112) を担当

Misc 【 display / non-display

  • 種実由来のプロテアーゼを用いた高齢者向け多機能食品の開発

    朝倉富子・田村倫子・舟木淳子

    浦上財団研究報告書   17   1 - 5   2010.03

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (other)   Publisher:浦上財団・食文化振興財団  

  • β-コングリシニン高生産/グリシニン欠失ダイズ種子におけるたん白質合成・分解ダイナミズムの検証

    朝倉富子・田村倫子・寺内かえで

    大豆たん白質研究   12   51 - 57   2009.10

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (other)   Publisher:不二たん白質研究振興財団  

  • β-グルコシダーゼの食品加工への利用のための基礎的研究

    西の明瑞穂・渡邉智美・田村倫子・江頭和佳子・朝倉富子・舟木淳子

    福岡女子大学人間環境学部紀要   40   1 - 5   2009.03

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (bulletin of university, research institution)   Publisher:福岡女子大学人間環境学部紀要  

  • 植物のアスパラギン酸プロテアーゼ ―その多様性と機能―

    朝倉富子・田村倫子・寺内かえで・阿部啓子

    化学と生物   46   702 - 209   2008.10

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:日本農芸化学会  

  • ヒトゲノムプロジェクト ―その技術と政治―

    寺内かえで・田村倫子

    広島工業大学紀要   42   237 - 245   2007.02

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (bulletin of university, research institution)   Publisher:広島工業大学紀要  

Scientific Research Funds Acquisition Results 【 display / non-display

  • アミラーゼ分泌酵母の発酵に関わる機能解析と豊かな食文化への食素材構築

    Grant number:22K02142  2022.04 - 2026.03

    科学研究費補助金  基盤研究(C)

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    Authorship:Principal investigator 

  • 蜂蜜から分離した酵母の高糖度耐性メカニズムの解明

    2016.04 - 2019.03

    科学研究費補助金  基盤研究(C)

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    Authorship:Principal investigator 

  • ラッカセイ種皮プロシアニジンの糖吸収抑制機能および抗菌メカニズムの解析

    2014.04 - 2016.03

    科学研究費補助金  若手研究(B)

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    Authorship:Principal investigator 

  • 食品の非可食部に由来するポリフェノールの脂質代謝調節

    2012.04 - 2014.03

    科学研究費補助金  若手研究(B)

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    Authorship:Principal investigator 

    食品の非可食部に由来するポリフェノールの脂質代謝調節

Other External Funds 【 display / non-display

  • 塩ストレス付与が青臭みの少ない大豆品種に与える効果 -収穫後の生 豆の機能性向上を目指して-

    Grant number:24D1  2024.04 - 2025.03

    公益財団法人ソルト・サイエンス研究財団  研究助成 

  • コメの安定した生産に寄与する酵素の研究 ~膜貫通型プロテアーゼの生理機能の解明と環境応答への関与~

    2023.07 - 2025.06

    民間財団等  公益財団法人エリザベス・アーノルド富士財団 

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    Authorship:Principal investigator  Grant type:Competitive

  • 細胞培養技術を用いて製造される食 肉のリスク評価手法に関する研究

    Grant number:JPCAFSC2022220  2022.11 - 2024.03

    内閣府食品安全委員会  食品安全委員会食品健康影響評価技術研究 

  • 短時間吸水により機能性を高めた大豆素材の開発とDNAマイクロアレイ解析による経時的特性評価

    2013.04 - 2014.03

    民間財団等  公益財団法人不二たん白質研究振興財団 

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    Authorship:Principal investigator  Grant type:Competitive

  • 発芽前の短時間吸水により機能性を高めた小麦素材の開発とそのDNAマイクロアレイ解析による経時特性の評価

    2012.06 - 2013.03

    民間財団等  公益財団法人エリザベス・アーノルド富士財団 

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    Authorship:Principal investigator  Grant type:Competitive

Presentations 【 display / non-display

  • 培養肉の安全性評価の提案 ―トランスクリプトーム解析の視点からー

    樗澤怜,田中龍一郎,山中久美子,清水達也,五十君靜信,田村倫子

    日本食品化学学会 第30回総会・学術大会  2024.05 

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    Event date: 2024.05

    Language:Japanese   Presentation type:Poster presentation  

    細胞培養技術を用いた食品、いわゆる培養肉の研究開発は加速的に発展し、世界各国で安全性の承認・販売事例が出てきている。我が国でも当該食品の開発が急速に進められているが、培養肉が従来の食肉に比べどのような特徴があるのか情報が乏しく、安全性評価の基準が定まっていない。そこで今回、培養肉製造の資源と市販の鶏肉とを、トランスクリプトームの手法で比較し、ここで見えてきた課題を通して安全性評価基準の礎を提案することを目的とした。

  • Differences between muscle stem cells for producing cultured meat and broiler chicken from the perspective of transcriptomics International coauthorship

    2024.03 

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    Event date: 2024.03

    Language:English   Presentation type:Oral presentation (general)  

    Cultured meat has recently been on the market in some countries. In Japan, the development of cultured meat products is proceeding rapidly. It is important to assess the safety of the novel food before its introduction to the market. However, little information is available on the characteristics of the final production compared to conventional meat. In this study, we performed transcriptome analysis to compare differentially expressed genes between stem cells which is used in the former step in the process of production of cultured meat and commercially available meat.
    Fibroblasts and myoblasts were isolated from embryo thigh muscle in chicken eggs. Three aliquots of cells at passage three to five were used as samples. Chicken thigh meat from 40-day-old broiler chicks were purchased from a local store. Total RNA was extracted and applied next-generation sequencing.
    A total of 1438 differentially expressed genes (DEGs) out of 25440 genes were found between fibroblasts and broiler chicks. GO enrichment analysis revealed that DEGs associated with negative regulation of cell adhesion and cell cycle regulation were up-regulated in fibroblasts. In contrast, DEGs related to muscle cell metabolisms were down-regulated in fibroblasts. The same tendency was shown between myoblasts and broiler chicks.

  • 蜂蜜酵母Zygosaccharomyces mellisの高糖度耐性遺伝子の探索

    田村倫子、笠原浩司、桑村麻由里、阿久澤さゆり、村清司

    日本農芸化学会  2016.03 

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    Event date: 2016.03

    Language:Japanese   Presentation type:Poster presentation  

    Venue:札幌  

  • 重合度の異なるラッカセイ種皮プロシアニジンの糖吸収抑制作用

    田村倫子, 小澤恵実, 小林彰子, 渡辺寛人, 荒井綜一, 村 清司

    日本食品科学工学会 第61回大会  2014.08 

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    Event date: 2014.08

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 小麦のポストハーベスト品質を向上させる短時間吸水の効果

    田村倫子,阿久澤さゆり,村清司,荒井綜一

    日本食品科学工学会平成26年度関東支部大会  2014.03 

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    Event date: 2014.03

    Language:Japanese   Presentation type:Poster presentation  

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Teaching Experience 【 display / non-display

  • 食品加工保蔵学

  • 植物生理学

  • 遺伝子工学