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MORI Kikue Assistant Professor |
Degree 【 display / non-display 】
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博士（医学） ( 2017.03 東海大学 )
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修士（食品栄養学） ( 2014.03 東京農業大学 )
Employment Record in Research 【 display / non-display 】
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Tokyo University of Agriculture Faculty of Applied Bio-Science Department of Nutritional Science Assistant Professor
2018.04
Professional Memberships 【 display / non-display 】
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日本栄養改善学会
2018
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日本栄養・食糧学会
2018
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公益社団法人 日本栄養士会
2017.11
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日本脂質栄養学会
2017.05
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日本循環器学会
2014.04
Papers 【 display / non-display 】
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Thirty-Year Trends in the Prevalence and Severity of Diabetic Retinopathy at the First Visit in Patients with Untreated Type 2 Diabetes Mellitus Reviewed International journal
Tetsuya Kubota, Kikue Todoroki-Mori, Masahiko Iwamoto, Toshiko Kobori, Takako Kikuchi, Tazu Tahara, Yukiko Onishi, Michihiro Araki, Masato Kasuga, Yoko Yoshida
Ophthalmic Epidemiology 2024.08
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
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Sustained Myocarditis following Messenger RNA Vaccination against Coronavirus Disease 2019: Relation to Neutralizing Antibody and Amelioration by Low-Dose Booster Vaccination Reviewed International journal
Koji Miyazaki, Toshiharu Fujii, Kikue Mori, Ryuichi Tamimoto, Hirofumi Nagamatsu, Tsutomu Murakami, Yasunori Cho, Shinya Goto and Hidezo Mori
Journal of Clinical Medicine 12 ( 4 ) 2023.02
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.3390/jcm12041421
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Pathophysiological analysis of renal fibrosis in SD rats treated with unilateral nephrectomy and fed a high phosphorus die
SEKIGUCHI Keita, MORI Kikue, UNO Kinuko, KEMURIYAMA Noriko, KATSUMATA Shinichi, MATSUZAKI Hiroshi, MIYAJIMA Katsuhiro
Annual Meeting of the Japanese Society of Toxicology 50.1 ( 0 ) P1-072S 2023
Language：Japanese Publisher：The Japanese Society of Toxicology
<p>[Background] Excessive phosphorus intake causes tubular damage with calcification and fibrosis in the tubular interstitium. The changes are known to correlate with decreased renal function, however, the mechanism by which fibrosis occurs is still unknown. In this study, we attempted a histopathological analysis of kidney fibrosis induced by feeding the short-term high-phosphate diet. [Material and Methods] 5-week-old male SD rats were treated with UNx and fed 0.3% or 1.5% KH2PO4-containg diet for 21 days. In the control group, SD rats were sham-operated and fed 0.3% KH2PO4 under the same conditions. Urine was sampled before the day of sacrifice and blood and kidney were sampled at necropsy. [Results] Blood and urine biochemical examinations showed decreased Ccr, increased U-ALB and urinary L-FABP in the UNx+1.5% group. Histopathological findings were observed as follows in the same group: moderate to severe regenerated tubules and inflammatory cell infiltration, slight to severe tubular dilatation and interstitial fibrosis, very slight to moderate calcification. IHC staining revealed CD44 expression in the renal tubular epithelium and increased α-SMA-positive cells in the interstitial area. [Discussion] Severe renal tubular damage with calcification and interstitial fibrosis was induced by UNx and fed 1.5% KH2PO4 in SD rats. Furthermore, CD44 was inferred to be expressed in the regenerating tubular epithelium, indicating that its expression is associated with progression of fibrosis. These results suggested that a high-phosphorus diet may promote the worsening of CKD.</p>
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Effects of dietary phosphorus concentration and phosphate salt form on renal tubule function in unilateral nephrectomized rats Reviewed International journal
Nutrition and Health 2022.08
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
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Mori Kikue, Katsumata Shinichi, Matsuzaki Hiroshi
JOURNAL OF JAPAN HEALTH MEDICINE ASSOCIATION 30 ( 2 ) 218 - 222 2021.07
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：JAPAN HEALTH MEDICINE ASSOCIATION
<p>Excessive consumption of phosphorus is one of the risk factors in the progression of kidney disease, whereas the effects of different dietary phosphate salts are unclear. In this study, we examined the effects of different dietary phosphate salts containing potassium dihydrogenphosphate (KH<sub>2</sub>PO<sub>4</sub>) and potassium tripolyphosphate (K<sub>5</sub>P<sub>3</sub>O<sub>10</sub>) on kidney function in unilateral nephrectomized (UNx) rats fed the normal dietary phosphorus concentration. Male UNx Sprague-Dawley rats were divided into two groups, and fed the diet containing KH<sub>2</sub>PO<sub>4</sub> (UNx-KH) and K<sub>5</sub>P<sub>3</sub>O<sub>10</sub> (UNx-KP) as dietary phosphate salts, respectively. The markers of kidney function, the serum urea nitrogen concentration, creatinine clearance, urinary creatinine, albumin, L-type fatty acid binding protein and N-acetyl-β-D-glucosaminidase activity were not significantly different between the groups. Serum phosphorus concentration was lower in UNx-KP than in UNx-KH. On the other hand, serum calcium, potassium, fibroblast growth factor 23 and parathyroid hormone concentration in the groups had no significant difference. These results suggest that KH<sub>2</sub>PO<sub>4</sub> and K<sub>5</sub>P<sub>3</sub>O<sub>10</sub> as dietary phosphate salts at the normal phosphorus levels had no different effects on kidney function in UNx rats.</p>
Books and Other Publications 【 display / non-display 】
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新訂生理学実習書
盛英三, 静間徹, 福山直人, 田中千陽, 軣木喜久江（ Role： Joint author , 各統計処理についての確認と校正）
南江堂 2013.09
Total pages：295 Responsible for pages：266-285 Language：Japanese Book type：Scholarly book
生理学実験における実験データの統計処理についてまとめた。
B4版 全295ページ
Misc 【 display / non-display 】
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食餌性マグネシウム欠乏と生体内リン代謝調節 Invited Reviewed
松﨑広志、盛喜久江
マグネシウム 2020
Language：English Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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高齢者の栄養管理とリハビリテーション「加齢による栄養状態と身体機能の変化」
若菜宣明、軣木喜久江、本間和宏、 田中越郎
理療 41 ( 4 ) 64 - 71 2012.02
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
日本人の食事摂取基準を用いて高齢者におけるエネルギーとたんぱく質の考え方や、加齢による身体状況および栄養状態の変化についての概説を行った。
Presentations 【 display / non-display 】
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高齢者における不飽和脂肪酸の欠乏と薬剤治療における効果
軣木喜久江, 池谷義守, 福井早矢人, 田中千陽, 関根佳織, 静間徹, 福山直人, 盛英三
第58回日本老年医学会学術集会 2016.06 日本老年医学会
Event date： 2016.06
Language：Japanese Presentation type：Oral presentation (general)
Venue：金沢石川県立音楽堂
後期高齢者にエパデール製剤を投与することで上室性不整脈と生命予後の改善が見られた。
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後期高齢者における脳白質病変と血行動態諸標の関連
軣木喜久江, 池谷義守, 福井早矢人, 柳町徳春, 岡崎隆，関根佳織, 静間徹, 田中越郎, 福山直人, 盛英三
第58回日本老年医学会学術集会 2016.06 日本老年医学会
Event date： 2016.06
Language：Japanese Presentation type：Oral presentation (general)
Venue：金沢石川県立音楽堂
後期高齢者の脳MRMによる白質病変の重症度と身体活動能力やヘモグロビン、血圧などの血行動態との関連が認められた。
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グループホーム入居後期高齢者の医学、栄養学、看護学的特徴： 循環器外来通院者および特別養護老人ホーム入居者との対比
軣木喜久江, 特別養護老人ホーム恒春の丘 看護課, 多聞 慶恵子, 茨木 英里, 信岡 陽子, 吉中 信之, 寺門 丈子, 福井 早矢人, 池谷 義守, 静間 徹, 福山 直人, 盛 英三
第80回日本循環器学会学術集会 2016.03 日本循環器学会
Event date： 2016.03
Language：Japanese Presentation type：Oral presentation (general)
Venue：仙台市民会館
グループホームと特養の高齢者（施設入所者）と、外来通院患者の臨床データの比較を行い、施設入所者では魚の摂取量が低いことが原因で、血中エイコサペンタエン酸濃度が低いことが示唆された。
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A Collaborative Approach in Medical and Nutritional Care in a Community toward Better Vital Prognosis in the Latter-Stage Elderly
Kikue Todoroki, Yoshimori Ikeya, Sayato Fukui, Chiharu Tanaka, Kaori Sekine, Toru Shizuma, Naoto Fukuyama, Hidezo Mori
第81回日本循環器学会学術集会 2016.03 日本循環器学会
Event date： 2016.03
Language：English Presentation type：Oral presentation (general)
Venue：仙台国際センター
グループホームという地域包括ケアシステムに位置するサービスが提供するケアの効果を報告した。
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The analysis of the polyunsaturated fatty acids and the incidences of supraventricular arrhythmias of the elderly in Group Home
Todoroki Kikue, Ikeya Yoshimori, Tanaka Etsuro, Fukuyama Naoto, Mori Hidezo
第91回日本生理学会大会 2014.03 日本生理学会
Event date： 2014.03
Language：English Presentation type：Oral presentation (general)
Venue：鹿児島大学
グループホーム入居者の血中多価不飽和脂肪酸値とホルタ―心電図による上室性不整脈の関連を調べた。