研究者詳細 - 遠藤　明仁

論文 - 遠藤　明仁

分割表示 >> ／全件表示 118 件中 1 - 118 件目

The Effects of 1-Kestose on the Abundance of Inflammation-Related Gene mRNA in Adipose Tissue and the Gut Microbiota Composition in Rats Fed a High-Fat Diet

KURAMITSU Kento, KADOTA Yoshihiro, WATANABE Ayako, ENDO Akihito, SHIMOMURA Yoshiharu, KITAURA Yasuyuki

Journal of Nutritional Science and Vitaminology 70 ( 4 ) 311 - 317 2024年08月

記述言語：英語出版者・発行元：Center for Academic Publications Japan

Chronic inflammation in adipose tissue is thought to contribute to insulin resistance, which involves the gut microbiota. Our previous studies have demonstrated that ingestion of 1-kestose can alter the gut microbiota composition, increase cecal butyrate levels, and improve insulin resistance in Otsuka Long-Evans Tokushima Fatty (OLETF) rats. Additionally, we found that 1-kestose supplementation ameliorated insulin resistance in obese rat models fed a high-fat diet (HFD), although the effects of 1-kestose on the abundance of inflammation-related gene in adipose tissue and gut microbiota composition in these rats were not explored. This study aimed to investigate the impact of 1-kestose on these parameters in HFD-fed rats, compared to OLETF rats. Male Sprague-Dawley rats were divided into two dietary groups, control or HFD, for 19 wk. Each group was further subdivided to receive either tap water or tap water supplemented with 2% (w/v) 1-kestose throughout the study. We evaluated gene expression in adipose tissue, as well as short-chain fatty acids (SCFAs) levels and microbial composition in the cecum contents. 1-Kestose intake restored the increased relative abundance of tumor necrosis factor (Tnf) mRNA in adipose tissue and the reduced level of butyrate in the cecum contents of HFD-fed rats to those observed in control diet-fed rats. Additionally, 1-kestose consumption changed the composition of the gut microbiota, increasing Butyricicoccus spp., decreasing UGC-005 and Streptococcus spp., in the cecum contents of HFD-fed rats. Our findings suggest that 1-kestose supplementation reduces adipose tissue inflammation and increases butyrate levels in the gut of HFD-fed rats, associated with changes in the gut microbiota composition, distinct from those seen in OLETF rats.

DOI： 10.3177/jnsv.70.311

PubMed

Technique for assessing the astringency of persimmon fruit by measuring the liposome aggregation

Kera Kota, Makino Shohei, Takeda Risako, Shimeno Aoi, Hojo Masaya, Hamasaki Sadahiro, Endo Akihito, Iijima Masumi, Nakayama Tsutomu

Food Science and Technology Research 30 ( 2 ) 195 - 204 2024年

記述言語：英語出版者・発行元：Japanese Society for Food Science and Technology

The astringency of persimmon fruits is a significant factor for consumers and the nutritional industry. To date, astringents, such as polyphenols, specifically persimmon condensed tannins, have been assessed using polyphenol quantification assays, such as the Folin–Ciocalteu method, based on their reducing power. However, these methods are influenced by the presence of other reducing substances. In this study, we developed a cost-effective liposome turbidity analysis using a portable visible spectrophotometer based on the interaction between liposomes and astringents. Authentic astringents, such as catechins and theaflavin-3-O-gallate, were analyzed, and their half-maximal effective concentrations (EC50) were calculated. These results indicated that the affinity to the membrane was similar to that of astringency, as determined by sensory analysis. Additionally, the EC50 values of partially purified tannins from non-astringent and astringent persimmons were calculated. In conclusion, we determined the application methods to assess astringent persimmon fruits with and without the removal of astringency.

DOI： 10.3136/fstr.fstr-d-23-00189

Faecalibacterium hominis Liu et al. 2023 is a later heterotypic synonym of Faecalibacterium duncaniae Sakamoto et al. 2022

Mitsuo Sakamoto, Naomi Sakurai, Hiroki Tanno, Takao Iino, Moriya Ohkuma, Akihito Endo

International Journal of Systematic and Evolutionary Microbiology 73 ( 8 ) 2023年08月

出版者・発行元：Microbiology Society

<jats:p>A strain of the recently validated species <jats:italic>
<jats:named-content content-type="species">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.42294" xlink:type="simple">Faecalibacterium hominis</jats:ext-link>
</jats:named-content>
</jats:italic> shares 99.0 % 16S rRNA gene sequence similarity with the type strain of <jats:italic>
<jats:named-content content-type="species">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.42636" xlink:type="simple">Faecalibacterium duncaniae</jats:ext-link>
</jats:named-content>
</jats:italic>. The aim of this study was to evaluate the taxonomic relationship between <jats:italic>
<jats:named-content content-type="species">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.42294" xlink:type="simple">F. hominis</jats:ext-link>
</jats:named-content>
</jats:italic> and <jats:italic>F. duncaniae. F. duncaniae</jats:italic> JCM 31915<jats:sup>T</jats:sup> showed 73.0 % digital DNA–DNA hybridization (dDDH) value with <jats:italic>
<jats:named-content content-type="species">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.42294" xlink:type="simple">F. hominis</jats:ext-link>
</jats:named-content>
</jats:italic> JCM 39347<jats:sup>T</jats:sup>. The average nucleotide identity (ANI) value between these two strains was 96.7 %. These results indicate that <jats:italic>
<jats:named-content content-type="species">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.42636" xlink:type="simple">F. duncaniae</jats:ext-link>
</jats:named-content>
</jats:italic> JCM 31915<jats:sup>T</jats:sup> and <jats:italic>
<jats:named-content content-type="species">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.42294" xlink:type="simple">F. hominis</jats:ext-link>
</jats:named-content>
</jats:italic> JCM 39347<jats:sup>T</jats:sup> represent members of the same species. Based on these data, we propose <jats:italic>
<jats:named-content content-type="species">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.42294" xlink:type="simple">Faecalibacterium hominis</jats:ext-link>
</jats:named-content>
</jats:italic> as a later heterotypic synonym of <jats:italic>
<jats:named-content content-type="species">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.42636" xlink:type="simple">Faecalibacterium duncaniae</jats:ext-link>
</jats:named-content>
</jats:italic>. An emended description is provided.</jats:p>

DOI： 10.1099/ijsem.0.005995

New gene markers for classification and quantification ofFaecalibacteriumspp. in the human gut

Hiroki Tanno, Jean-Marc Chatel, Rebeca Martin, Denis Mariat, Mitsuo Sakamoto, Masao Yamazaki, Seppo Salminen, Miguel Gueimonde, Akihito Endo

FEMS Microbiology Ecology 99 ( 5 ) 2023年03月

出版者・発行元：Oxford University Press (OUP)

<jats:title>Abstract</jats:title><jats:p>Faecalibacterium prausnitzii is a promising biomarker of a healthy human microbiota. However, previous studies reported the heterogeneity of this species and found the presence of several distinct groups at the species level among F. prausnitzii strains. Our recent study revealed that methods previously developed for quantification of F. prausnitzii were not specific to the species level because of the heterogeneity within the F. prausnitzii species and the application of 16S rRNA gene, which is an invalid genetic marker for the species. Therefore, previously available data failed to provide information on different groups, which limits our understanding of the importance of this organism for host health. Here, we propose an alternative gene marker for quantification of F. prausnitzii-related taxa. A total of nine group-specific primer pairs were designed by targeting rpoA gene sequences. The newly developed rpoA-based qPCR successfully quantified targeted groups. Application of the developed qPCR assay in six healthy adults revealed marked differences in abundance and prevalence among the different targeted groups in stool samples. The developed assay will facilitate detailed understanding of the impact of Faecalibacterium populations at the group level on human health and to understand the links between depletion of specific groups in Faecalibacterium and different human disorders.</jats:p>

DOI： 10.1093/femsec/fiad035

PubMed

Microbial composition and metabolic profiles during machine-controlled intra-factory fermentation of cocoa beans harvested in semitropical area of Japan

NISHIMURA Hiroya, SHIWA Yuh, TOMITA Satoru, ENDO Akihito

Bioscience of Microbiota, Food and Health advpub ( 0 ) 29 - 42 2023年

記述言語：英語出版者・発行元：BMFH Press

Cocoa bean fermentation is typically performed in a spontaneous manner on farms in tropical countries or areas and involves several microbial groups. Metabolism by microbes markedly affects the quality of cocoa beans fermented and the chocolate produced thereof. The present study characterized the microbiota and their metabolic profiles in temperature- and humidity-controlled intra-factory cocoa fermentation in a semitropical area of Japan. Although environmental factors were uniform, the microbiota of cocoa beans subjected to intra-factory fermentation was not stable between tests, particularly in terms of the cell count levels and species observed. Fermentation was sometimes delayed, and fermenting microbes were present at very low levels after 24 hr of fermentation. Due to the unstable microbiota, the profiles of water-soluble compounds differed between tests, indicating the unstable qualities of the fermented cocoa beans. These results suggest the necessity of starter cultures not only in on-farm fermentation but also in machine-controlled intra-factory cocoa fermentation.

DOI： 10.12938/bmfh.2023-036

Ribotype‐dependent growth inhibition and promotion by erythritol in Cutibacterium acnes

Tadashi Fujii, Takumi Tochio, Akihito Endo

Journal of Cosmetic Dermatology 21 ( 10 ) 5049 - 5057 2022年05月

出版者・発行元：Wiley

<jats:title>Abstract</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>The close balance between <jats:italic>Cutibacterium acnes</jats:italic> and the skin flora, particularly between <jats:italic>C</jats:italic>. <jats:italic>acnes</jats:italic> phylotypes, has been suggested to play an important role in the onset of acne. <jats:italic>C</jats:italic>. <jats:italic>acnes</jats:italic> has been classified into ribotypes (RTs) based on polymorphisms in its 16S rRNA sequence, with RT4 and RT5 being associated with the onset of acne and RT6 with healthy skin.</jats:p></jats:sec><jats:sec><jats:title>Aims</jats:title><jats:p>The present study investigated the impact of erythritol on the growth of <jats:italic>C</jats:italic>. <jats:italic>acnes</jats:italic> strains classified into different RTs and attempted to elucidate the molecular mechanisms underlying its effects.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Culturing tests were performed on several RTs of <jats:italic>C. acnes</jats:italic> with or without erythritol. A transcriptional analysis of HM554 (RT6) and HM514 (RT5) was also conducted.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The growth of RT2 and RT6, RTs associated with healthy skin, was significantly promoted in a medium containing 10% (W/W) erythritol, whereas that of RT1, RT3, RT4, RT5, and RT8, RTs associated with the development of acne, was inhibited. A RNA‐seq analysis of HM554 showed that the expression of six genes (<jats:italic>EIGs</jats:italic>) potentially involved in carbohydrate metabolism was strongly induced by the presence of 10% erythritol (Log<jats:sub>2</jats:sub> fold change >2.0 and <jats:italic>p</jats:italic>‐value <0.05). A comparative expression analysis by qPCR revealed that <jats:italic>EIGs</jats:italic> other than <jats:italic>g3pD</jats:italic> were strongly induced by erythritol in HM514, similar to HM554, whereas <jats:italic>g3pD</jats:italic> was only slightly induced.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Erythritol inhibited the growth of RTs associated with acne and promoted that of RTs associated with healthy skin. The enzyme encoded by <jats:italic>g3pD</jats:italic> may play an important role in the metabolism of erythritol and the dissolution of its growth inhibitory effects on <jats:italic>C</jats:italic>. <jats:italic>acnes</jats:italic>.</jats:p></jats:sec>

DOI： 10.1111/jocd.14958

PubMed

Genome-based, phenotypic and chemotaxonomic classification of Faecalibacterium strains: proposal of three novel species Faecalibacterium duncaniae sp. nov., Faecalibacterium hattorii sp. nov. and Faecalibacterium gallinarum sp. nov.

Mitsuo Sakamoto, Naomi Sakurai, Hiroki Tanno, Takao Iino, Moriya Ohkuma, Akihito Endo

International Journal of Systematic and Evolutionary Microbiology 72 ( 4 ) 35416766 2022年04月

出版者・発行元：Microbiology Society

<jats:p>
<jats:italic>
<jats:named-content content-type="species">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.4089" xlink:type="simple">Faecalibacterium prausnitzii</jats:ext-link>
</jats:named-content>
</jats:italic> is one of the most important butyrate-producing bacteria in the human gut. Previous studies have suggested the presence of several phylogenetic groups, with differences at the species level, in the species, and a taxonomic re-evaluation is thus essential for further understanding of ecology of the important human symbiont. Here we examine the phenotypic, physiological, chemotaxonomic and phylogenomic characteristics of six <jats:italic>
<jats:named-content content-type="species">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.4089" xlink:type="simple">F. prausnitzii</jats:ext-link>
</jats:named-content>
</jats:italic> strains (BCRC 81047<jats:sup>T</jats:sup>=ATCC 27768<jats:sup>T</jats:sup>, A2-165<jats:sup>T</jats:sup>=JCM 31915<jats:sup>T</jats:sup>, APC918/95b=JCM 39207, APC942/30−2=JCM 39208, APC924/119=JCM 39209 and APC922/41−1<jats:sup>T</jats:sup>=JCM 39210<jats:sup>T</jats:sup>) deposited in public culture collections with two reference strains of <jats:italic>
<jats:named-content content-type="species">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.40325" xlink:type="simple">Faecalibacterium butyricigenerans</jats:ext-link>
</jats:named-content>
</jats:italic> JCM 39212<jats:sup>T</jats:sup> and <jats:italic>
<jats:named-content content-type="species">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.40326" xlink:type="simple">Faecalibacterium longum</jats:ext-link>
</jats:named-content>
</jats:italic> JCM 39211<jats:sup>T</jats:sup>. <jats:italic>
<jats:named-content content-type="genus">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.4088" xlink:type="simple">Faecalibacterium</jats:ext-link>
</jats:named-content>
</jats:italic> sp. JCM 17207<jats:sup>T</jats:sup> isolated from caecum of broiler chicken was also included. Three strains of <jats:italic>
<jats:named-content content-type="species">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.4089" xlink:type="simple">F. prausnitzii</jats:ext-link>
</jats:named-content>
</jats:italic> (BCRC 81047<jats:sup>T</jats:sup>, JCM 39207 and JCM 39209) shared more than 96.6 % average nucleotide identity (ANI) and 69.6 % digital DNA–DNA hybridization (dDDH) values, indicating that the three strains are members of the same species. On the other hand, the remaining three strains of <jats:italic>
<jats:named-content content-type="species">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.4089" xlink:type="simple">F. prausnitzii</jats:ext-link>
</jats:named-content>
</jats:italic> (JCM 31915<jats:sup>T</jats:sup>, JCM 39208 and JCM 39210<jats:sup>T</jats:sup>) were clearly separated from the above three strains based on the ANI and dDDH values. Rather, JCM 39208 showed ANI and dDDH values over the cut-off values of species discrimination (>70 % dDDH and >95–96 % ANI) with <jats:italic>
<jats:named-content content-type="species">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.org/10.1601/nm.40326" xlink:type="simple">F. longum</jats:ext-link>
</jats:named-content>
</jats:italic> JCM 39211<jats:sup>T</jats:sup>, whereas JCM 31915<jats:sup>T</jats:sup>, JCM 39210<jats:sup>T</jats:sup> and JCM 17207<jats:sup>T</jats:sup> did not share dDDH and ANI values over the currently accepted cut-off values with any of the tested strains, including among them. Furthermore, the cellular fatty acid patterns of these strains were slightly different from other <jats:italic>
<jats:named-content content-type="species">
<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://doi.o ...

DOI： 10.1099/ijsem.0.005379

16S rRNA gene sequence diversity in Faecalibacterium prausnitzii-complex taxa has marked impacts on quantitative analysis

Hiroki Tanno, Shintaro Maeno, Seppo Salminen, Miguel Gueimonde, Akihito Endo

FEMS Microbiology Ecology 98 ( 1 ) fiac004 2022年01月

出版者・発行元：Oxford University Press (OUP)

<jats:title>Abstract</jats:title>
<jats:p>Faecalibacterium prausnitzii has been suggested as a biomarker of a healthy microbiota in human adults. Here, we report a taxonomic study of F. prausnitzii using genomic information and evaluation of the quantitative real-time PCR (qPCR) assay by focusing on specific primers to quantify its population. Average nucleotide identity values revealed that strains deposited as F. prausnitzii in a public database were separated into eight genomogroups with significant differences at the species level. A total of six of the 10 primer pairs used in the previous studies for qPCR of F. prausnitzii contained sequence mismatches to 16S rRNA gene sequences of the tested strains with markedly different levels by in silico analysis. In vitro primer evaluation by qPCR generally agreed with the in silico analysis, and markedly reduced amount of DNA was recorded by qPCR in combination with the primer pairs containing sequence mismatches. The present study demonstrated that a part of the accumulated knowledge on F. prausnitzii is maybe based on biased results.</jats:p>

DOI： 10.1093/femsec/fiac004

PubMed

Viable fructophilic lactic acid bacteria present in honeybee-based food products 査読あり

Takatani N, Endo A.

FEMS Microbiology Letters 2021年12月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

食品 (新鮮ハチミツ) 中のフルクトフィリック乳酸菌の生菌での分布を明らかにすることで、フルクトフィリック乳酸菌の安全性を明らかにした。

Supplementation of 1-Kestose Modulates the Gut Microbiota Composition to Ameliorate Glucose Metabolism in Obesity-Prone Hosts

Ayako Watanabe, Takumi Tochio, Yoshihiro Kadota, Motoki Takahashi, Yasuyuki Kitaura, Hirohito Ishikawa, Takanori Yasutake, Masahiro Nakano, Hiroe Shinohara, Toru Kudo, Yuichiro Nishimoto, Yoshinori Mizuguchi, Akihito Endo, Yoshiharu Shimomura

Nutrients 13 ( 9 ) 2983 2021年08月

出版者・発行元：MDPI AG

<jats:p>Insulin resistance leads to the onset of medical conditions such as type 2 diabetes, and its development is associated with the alteration in the gut microbiota. Although it has been demonstrated that supplementation with prebiotics modulates the gut microbiota, limited evidence is available for effects of prebiotics on insulin resistance, especially for humans. We investigated the prebiotic effect of 1-kestose supplementation on fasting insulin concentration in obesity-prone humans and rats. In the preliminary study using rats, the hyperinsulinemia induced by high-fat diet was suppressed by intake of water with 2% (w/v) 1-kestose. In the clinical study using obese-prone volunteers, the fasting serum insulin level was significantly reduced from 6.5 µU/mL (95% CI, 5.5–7.6) to 5.3 (4.6–6.0) by the 12-week intervention with supplementation of 10 g 1-kestose/day, whereas it was not changed by the intervention with placebo (6.2 µU/mL (5.4–7.1) and 6.5 (5.5–7.6) before and after intervention, respectively). The relative abundance of fecal Bifidobacterium was significantly increased to 0.3244 (SD, 0.1526) in 1-kestose-supplemented participants compared to that in control participants (0.1971 (0.1158)). These results suggest that prebiotic intervention using 1–kestose may potentially ameliorate insulin resistance in overweight humans via the modulation of the gut microbiota. UMIN 000028824.</jats:p>

DOI： 10.3390/nu13092983

PubMed

Oligosaccharide Metabolism and Lipoteichoic Acid Production in Lactobacillus gasseri and Lactobacillus paragasseri

Tsukasa Shiraishi, Shintaro Maeno, Sayoko Kishi, Tadashi Fujii, Hiroki Tanno, Katsuaki Hirano, Takumi Tochio, Yasuhiro Tanizawa, Masanori Arita, Shin-ichi Yokota, Akihito Endo

Microorganisms 9 ( 8 ) 1590 2021年07月

出版者・発行元：MDPI AG

<jats:p>Lactobacillus gasseri and Lactobacillus paragasseri are human commensal lactobacilli that are candidates for probiotic application. Knowledge of their oligosaccharide metabolic properties is valuable for synbiotic application. The present study characterized oligosaccharide metabolic systems and their impact on lipoteichoic acid (LTA) production in the two organisms, i.e., L. gasseri JCM 1131T and L. paragasseri JCM 11657. The two strains grew well in medium with glucose but poorly in medium with raffinose, and growth rates in medium with kestose differed between the strains. Oligosaccharide metabolism markedly influenced their LTA production, and apparent molecular size of LTA in electrophoresis recovered from cells cultured with glucose and kestose differed from that from cells cultured with raffinose in the strains. On the other hand, more than 15-fold more LTA was observed in the L. gasseri cells cultured with raffinose when compared with glucose or kestose after incubation for 15 h. Transcriptome analysis identified glycoside hydrolase family 32 enzyme as a potential kestose hydrolysis enzyme in the two strains. Transcriptomic levels of multiple genes in the dlt operon, involved in D-alanine substitution of LTA, were lower in cells cultured with raffinose than in those cultured with kestose or glucose. This suggested that the different sizes of LTA observed among the carbohydrates tested were partly due to different levels of alanylation of LTA. The present study indicates that available oligosaccharide has the impact on the LTA production of the industrially important lactobacilli, which might influence their probiotic properties.</jats:p>

DOI： 10.3390/microorganisms9081590

Oligosaccharide Metabolism and Lipoteichoic Acid Production in Lactobacillus gasseri and Lactobacillus paragasseri 査読あり

Shiraishi T, Maeno S, Kishi S, Fujii T, Tanno H, Hirano K, Tochio T, Tanizawa Y, Arita M, Yokota SI, Endo A.

Microorganisms 2021年07月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

乳酸菌のオリゴ糖代謝が乳酸菌の機能性に与える影響を明らかにした

The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics 査読あり

Salminen S, Collado MC, Endo A, Hill C, Lebeer S, Quigley EMM, Sanders ME, Shamir R, Swann JR, Szajewska H, Vinderola G.

Nature Reiviews in Gastroengerology and Hepatology 2021年05月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

微生物の食品利用の新しい形であるポストバイオティクスについて、その定義を定めるとともに、利用例及び安全性について解説した

Niche-specific adaptation of Lactobacillus helveticus strains isolated from malt whisky and dairy fermentations

Yoshihiko Kido, Shintaro Maeno, Hiroki Tanno, Yuko Kichise, Yuh Shiwa, Akihito Endo

Microbial Genomics 7 ( 4 ) 2021年04月

出版者・発行元：Microbiology Society

DOI： 10.1099/mgen.0.000560

Host-Diet Effect on the Metabolism of Bifidobacterium

Maria Satti, Monica Modesto, Akihito Endo, Takeshi Kawashima, Paola Mattarelli, Masanori Arita

Genes 12 ( 4 ) 609 2021年04月

出版者・発行元：MDPI AG

<jats:p>Bifidobacterium has a diverse host range and shows several beneficial properties to the hosts. Many species should have co-evolved with their hosts, but the phylogeny of Bifidobacterium is dissimilar to that of host animals. The discrepancy could be linked to the niche-specific evolution due to hosts’ dietary carbohydrates. We investigated the relationship between bifidobacteria and their host diet using a comparative genomics approach. Since carbohydrates are the main class of nutrients for bifidobacterial growth, we examined the distribution of carbohydrate-active enzymes, in particular glycoside hydrolases (GHs) that metabolize unique oligosaccharides. When bifidobacterial species are classified by their distribution of GH genes, five groups arose according to their hosts’ feeding behavior. The distribution of GH genes was only weakly associated with the phylogeny of the host animals or with genomic features such as genome size. Thus, the hosts’ dietary pattern is the key determinant of the distribution and evolution of GH genes.</jats:p>

DOI： 10.3390/genes12040609

Niche-specific adaptation of Lactobacillus helveticus strains isolated from malt whisky and dairy fermentations 査読あり

Kido Y, Maeno S, Tanno H, Kichise Y, Shiwa Y, Endo A.

Microbial Genomics 2021年04月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

ウィスキーもろみ由来及び発酵乳由来の L. helveticus 菌株を比較することで、当該菌種の進化の様式について明らかにした

Species- and Age/Generation-Dependent Adherence of Bifidobacterium bifidum to Human Intestinal Mucus In Vitro

Gaku Harata, Kazutoyo Yoda, Ruipeng Wang, Kenji Miyazawa, Masayuki Sato, Fang He, Akihito Endo

Microorganisms 9 ( 3 ) 542 2021年03月

出版者・発行元：MDPI AG

<jats:p>Adhesion to intestinal mucus is the first event in the process by which intestinal microbes colonize the intestine. It plays a critical role in the initiation of interactions between gut microbes and host animals. Despite the importance, the adhesion properties of probiotics are generally characterized using porcine mucin; adhesion to human mucus has been poorly characterized. In the present study, human intestinal mucus samples were isolated from 114 fecal samples collected from healthy infants and adults. In initial screening, four out of the 13 beneficial microbes tested, including the type strain of Bifidobacterium bifidum, B. bifidum TMC3115, Lacticaseibacillus rhamnosus GG, and Bifidobacterium animalis subsp. lactis Bb12, showed strong adhesion abilities to human mucus. The type strain of B. bifidum and TMC3115 adhered more strongly to neonatal and infant mucus than to adult mucus, while L. rhamnosus GG and B. lactis Bb12 adhered more strongly to adult mucus than to infant mucus. Similar results were obtained for ten additional strains of B. bifidum. In conclusion, age/generation-related differences were observed in the adhesion properties of B. bifidum and other strains. A deeper symbiotic relationship may exist between infants, particularly neonates, and B. bifidum based on its enhanced adhesion to neonatal intestinal mucus.</jats:p>

DOI： 10.3390/microorganisms9030542

Unique niche-specific adaptation of fructophilic lactic acid bacteria and proposal of three Apilactobacillus species as novel members of the group 査読あり

Maeno S, Nishimura H, Tanizawa Y, Dicks L, Arita M, Endo A.

BMC Microbiology 2021年02月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

フルクトフィリック乳酸菌の収斂進化の様式をゲノム解析から明らかにした

Characterization of the microbiota and chemical properties of pork loins during dry aging

Akihito Endo, Ryosuke Koizumi, Yozo Nakazawa, Yuh Shiwa, Shintaro Maeno, Yoshihiko Kido, Tomohiro Irisawa, Yoshiki Muramatsu, Kotaro Tada, Masao Yamazaki, Takao Myoda

MicrobiologyOpen 10 ( 1 ) e1157 2021年01月

出版者・発行元：Wiley

<jats:title>Abstract</jats:title><jats:p>Dry aging (DA) allows for the storage of meat without packaging at 0 to 3°C for several weeks. It enhances the production of pleasant flavors, tenderness, and juiciness in meat. Due to the long storage period and roles of indigenous microbiota in the maturation of several meat products, the microbiota of DA meat is of interest in terms of microbial contributions and food hygiene but has not yet been characterized in detail. This study identified the microbiota of pork loins during DA using culturing and culture‐independent meta‐16S rRNA gene sequencing and elucidated its characteristics. The amounts of free amino acids and profiles of aroma‐active compounds were also monitored by high‐performance liquid chromatography and gas chromatography, respectively. The meta‐16S rRNA gene sequencing revealed that <jats:italic>Pseudomonas</jats:italic> spp. generally dominated the microbiota throughout DA; however, the culturing analysis showed marked changes in the species composition during DA. <jats:italic>Acinetobacter</jats:italic> spp. were the second most dominant bacteria before DA in the culture‐independent analysis but became a minor population during DA. The cell numbers of yeasts showed an increased tendency during DA, and <jats:italic>Debaryomyces hansenii</jats:italic> was the only microorganism isolated from all meat samples throughout DA. Well‐known foodborne pathogens were not observed in two microbiota analyses. The amounts of free amino acids were increased by DA, and the number of aroma‐active compounds and their flavor dilution values markedly changed during DA. Most microbial isolates showed positive reactions with proteolytic and lipolytic activities, suggesting their contribution to tenderness and aroma production in DA meats.</jats:p>

DOI： 10.1002/mbo3.1157

PubMed

Characterization of fructooligosaccharide metabolism and fructooligosaccharide-degrading enzymes in human commensal butyrate producers

Hiroki Tanno, Tadashi Fujii, Katsuaki Hirano, Shintaro Maeno, Takashi Tonozuka, Mitsuo Sakamoto, Moriya Ohkuma, Takumi Tochio, Akihito Endo

Gut Microbes 13 ( 1 ) 1 2021年01月

出版者・発行元：Informa UK Limited

Butyrate produced by gut microbiota has multiple beneficial effects on host health, and oligosaccharides derived from host diets and glycans originating from host mucus are major sources of its production. A significant reduction of butyrate-producing bacteria has been reported in patients with inflammatory bowel diseases and colorectal cancers. Although gut butyrate levels are important for host health, oligosaccharide metabolic properties in butyrate producers are poorly characterized. We studied the metabolic properties of fructooligosaccharides (FOSs) and other prebiotic oligosaccharides (i.e. raffinose and xylooligosaccharides; XOSs) in gut butyrate producers. 1-Kestose (kestose) and nystose, FOSs with degrees of polymerization of 3 and 4, respectively, were also included. Fourteen species of butyrate producers were divided into four groups based on their oligosaccharide metabolic properties, which are group A (two species) metabolizing all oligosaccharides tested, group F (four species) metabolizing FOSs but not raffinose and XOSs, group XR (four species) metabolizing XOSs and/or raffinose but not FOSs, and group N (four species) metabolizing none of the oligosaccharides tested. Species assigned to groups A and XR are rich glycoside hydrolase (GH) holders, whereas those in groups F and N are the opposite. In total, 17 enzymes assigned to GH32 were observed in nine of the 14 butyrate producers tested, and species that metabolized FOSs had at least one active GH32 enzyme. The GH32 enzymes were divided into four clusters by phylogenetic analysis. Heterologous gene expression analysis revealed that the GH32 enzymes in each cluster had similar FOS degradation properties within clusters, which may be linked to the conservation/substitution of amino acids to bind with substrates in GH32 enzymes. This study provides important knowledge to understand the impact of FOS supplementation on the activation of gut butyrate producers.

DOI： 10.1080/19490976.2020.1869503

PubMed

Characterization of fructooligosaccharide metabolism and fructooligosaccharide-degrading enzymes in human commensal butyrate producers 査読あり

Tanno H, Fujii T, Hirano K, Maeno S, Tonozuka T, Sakamoto M, Ohkuma M, Tochio T, Endo A.

Gut Microbes 2021年01月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

ヒト腸内酪酸産生菌のフルクトオリゴ糖代謝について、in vitro および in silico で明らかにした

Characterization of the microbiota and chemical properties of pork loins during dry aging 査読あり

Endo A, Koizumi R, Nakazawa Y, Shiwa Y, Maeno S, Kido Y, Irisawa T, Muramatsu Y, Tada K, Yamazaki M, Myoda T.

MicrobiologyOpen 2021年01月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

熟成肉の熟成過程における微生物の変遷を調べることで、熟成肉の安全性と熟成への微生物の寄与度を評価した

1-Kestose supplementation mitigates the progressive deterioration of glucose metabolism in type 2 diabetes OLETF rats 査読あり

Watanabe A, Kadota Y, Kamio R, Tochio T, Endo A, Shimomura Y, Kitaura Y.

Scientific Reports 2020年09月

記述言語：英語掲載種別：研究論文（学術雑誌）

オリゴ糖の一種であるケストースの機能性を2型糖尿病モデルラットを使って明らかにした。

Kunkecin A, a New Nisin Variant Bacteriocin Produced by the Fructophilic Lactic Acid Bacterium, Apilactobacillus kunkeei FF30-6 Isolated from Honey bees 査読あり

Zendo T, Ohashi C, Maeno S, Piao X, Salminen S, Sonomoto K, Endo A.

Frontiers in Microbiology 2020年09月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

フルクトフィリック乳酸菌が生産する新規のバクテリオシンである kunkecin A について報告した

Phylogenetic analysis of Leuconostoc and Lactobacillus species isolated from sugarcane processing streams 査読あり

Nel S, Davis SB, Endo A, Dicks LMT.

Microbiologyopen 2020年08月

記述言語：英語掲載種別：研究論文（学術雑誌）

砂糖製造過程で汚染の原因となる Lactobacillus 属細菌、Leuconostoc 属細菌を明らかにした。

PCR-based screening, isolation, and partial characterization of motile lactobacilli from various animal feces 査読あり

Suzuki S, Fujita K, Maeno S, Shiwa Y, Endo A, Yokota K, Igimi S, Kajikawa A.

BMC Microbiology 2020年06月

記述言語：英語掲載種別：研究論文（学術雑誌）

様々な動物糞便より、運動性乳酸菌の分離を行い、その諸性質を明らかにした

Characterisation of the bacterial community structures of sunki, a traditional unsalted pickle of fermented turnip leaves 査読あり

Tomita S, Watanabe J, Nakamura T, Endo A, Okada S.

Journal of Bioscience and Bioengineering 2020年05月

記述言語：英語掲載種別：研究論文（学術雑誌）

長野県の伝統的漬物すんきの発酵に関与する微生物を明らかにした

乳酸菌の分類・同定法の変遷とLactobacillus 属再分類の動き招待あり

遠藤明仁

日本乳酸菌学会誌 2020年04月

担当区分：筆頭著者記述言語：日本語掲載種別：研究論文（学術雑誌）

最新の乳酸菌分類事情について解説した。

乳酸菌の分類・同定法の変遷と Lactobacillus 属再分類の動き

遠藤明仁

日本乳酸菌学会誌 31 ( 1 ) 3 - 9 2020年03月

記述言語：日本語出版者・発行元：日本乳酸菌学会

乳酸菌はその機能性と安全性から、古くから産業利用のための研究が広く行われてきた。その一方で、乳酸菌の分類および同定に対する関心と研究は、昨今減少傾向にある。しかし、食品等への利用の際にはその菌株の正確な学名が必要になるため、乳酸菌の分類と同定は応用のためにも重要である。本総説では、これまでの乳酸菌の分類および同定法の変遷と共に、昨今話題となっている Lactobacillus 属再分類の動きについて解説する。

DOI： 10.4109/jslab.31.3

CiNii Articles

Kestose supplementation exerts bifidogenic effect within fecal microbiota and increases fecal butyrate concentration in dogs 査読あり

Ide K, Shinohara M, Yamagishi S, Endo A, Nishifuji K, Tochio T.

The Journal of Veterinary Medical Science 2020年01月

記述言語：英語掲載種別：研究論文（学術雑誌）

犬におけるオリゴ糖の健康効果を明らかにした。

In Vitro Evaluation of Different Prebiotics on the Modulation of Gut Microbiota Composition and Function in Morbid Obese and Normal-Weight Subjects 査読あり

Nogacka AM, Salazar N, Arboleya S, Ruas-Madiedo P, Mancabelli L, Suarez A, Martinez-Faedo C, Ventura M, Tochio T, Hirano K, Endo A, G de Los Reyes-Gavilán C, Gueimonde M

International Journal of Molecular Sciences 2020年01月

記述言語：英語掲載種別：研究論文（学術雑誌）

様々なオリゴ糖の腸内細菌活性化効果を、複合系を用いた解析により明らかにした

Fermented foods in a global age: East meets West

Jyoti Prakash Tamang, Paul D. Cotter, Akihito Endo, Nam Soo Han, Remco Kort, Shao Quan Liu, Baltasar Mayo, Nieke Westerik, Robert Hutkins

Comprehensive Reviews in Food Science and Food Safety 19 ( 1 ) 184 - 217 2020年01月

出版者・発行元：Wiley

<jats:title>Abstract</jats:title><jats:p>Fermented foods and alcoholic beverages have long been an important part of the human diet in nearly every culture on every continent. These foods are often well‐preserved and serve as stable and significant sources of proteins, vitamins, minerals, and other nutrients. Despite these common features, however, many differences exist with respect to substrates and products and the types of microbes involved in the manufacture of fermented foods and beverages produced globally. In this review, we describe these differences and consider the influence of geography and industrialization on fermented foods manufacture. Whereas fermented foods produced in Europe, North America, Australia, and New Zealand usually depend on defined starter cultures, those made in Asia and Africa often rely on spontaneous fermentation. Likewise, in developing countries, fermented foods are not often commercially produced on an industrial scale. Although many fermented products rely on autochthonous microbes present in the raw material, for other products, the introduction of starter culture technology has led to greater consistency, safety, and quality. The diversity and function of microbes present in a wide range of fermented foods can now be examined in detail using molecular and other omic approaches. The nutritional value of fermented foods is now well‐appreciated, especially in resource‐poor regions where yoghurt and other fermented foods can improve public health and provide opportunities for economic development. Manufacturers of fermented foods, whether small or large, should follow Good Manufacturing Practices and have sustainable development goals. Ultimately, preferences for fermented foods and beverages depend on dietary habits of consumers, as well as regional agricultural conditions and availability of resources.</jats:p>

DOI： 10.1111/1541-4337.12520

PubMed

Fermented foods in a global age: east meets west. 査読あり

Tamang, J.P., Cotter P., Endo A., Han N.S., Kort R., Liu S.Q., Mayo B., Westerik N., Hutkins R.

Comprehensive Reviews in Food Science and Food Safety 2020年

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

アジアを中心とした発酵食品の製造にかかわる微生物について解説した

Kestose supplementation exerts bifidogenic effect within fecal microbiota and increases fecal butyrate concentration in dogs

IDE Kaori, SHINOHARA Mikako, YAMAGISHI Shohei, ENDO Akihito, NISHIFUJI Koji, TOCHIO Takumi

Journal of Veterinary Medical Science 82 ( 1 ) 1 - 8 2020年

記述言語：英語出版者・発行元：JAPANESE SOCIETY OF VETERINARY SCIENCE

Kestose, a fructooligosaccharide (FOS) with one fructose monomer linked to sucrose, is a key component of the prebiotic activity of FOS. This study aimed to evaluate the prebiotic potential of Kestose in terms of the impact on population change in the intestinal microbiota and fecal short-chain fatty acid (SCFA) concentration in dogs. Kestose 2 g per dog was administered daily with conventional diet to 6 healthy, adult beagle dogs for 8 weeks followed by 4 weeks of follow-up period without Kestose supplementation. Fresh fecal samples were obtained before and every 4 weeks until the end of the follow-up period. Genomic DNA extracted from the fecal samples was subjected to 16S rRNA gene analysis using next generation sequencer and to quantitative polymerase chain reaction (qPCR). Fecal acetate, propionate, butyrate, lactate and ethanol concentrations were measured by high-performance liquid chromatography. 16S rRNA gene analysis and qPCR showed increasing trend of genus Bifidobacterium after Kestose supplementation while genera Bacteroides and Sutterella decreased. Clostridium perfringens decreased below the detection limit within first 4 weeks after starting Kestose supplementation. Fecal butyrate concentration was significantly increased at week 8 and returned to the base level after 4 weeks of the washing period. To the best of our knowledge, this is the first study to reveal effect of Kestose on the populational changes in fecal microbiota and fecal butyrate concentration in dogs.

DOI： 10.1292/jvms.19-0071

PubMed

CiNii Articles

ケストースが持つ多様な生理機能の解明と実用化に向けた取り組み

門田吉弘, 北浦靖之, 遠藤明仁, 栃尾巧

日本栄養・食糧学会誌 73 ( 4 ) 123 - 131 2020年

記述言語：日本語出版者・発行元：公益社団法人日本栄養・食糧学会

ケストースは, スクロースに1分子のフルクトースが結合した三糖のオリゴ糖である。我々は, プレバイオティクスとして流通している種々のオリゴ糖との比較試験を実施し, ケストースが, 最も幅広い腸内有用菌に対して良好な増殖を示すオリゴ糖であることを明らかにした。さらに, ケストースの継続的な摂取によって, アレルギー疾患や生活習慣病を予防・改善できる可能性も明らかにしており, ケストースが様々な生理機能を有するプレバイオティクスとして, 人々の健康維持に貢献できる可能性を示した。また, 我々は, ケストースの実用化に関する研究として, 工業的製造の際に使用される酵素の改良にも取り組んでいる。本稿では, ケストースによる有用菌増殖効果をはじめとして, ケストースが有する様々な生理機能および, 製造酵素の改良に向けた取り組みについて紹介する。

DOI： 10.4327/jsnfs.73.123

CiNii Articles

Differentiation between Bacillus amyloliquefaciens and Bacillus subtilis isolated from a South African sugarcane processing factory using ARDRA and rpoB gene sequencing. 査読あり

Nel S, Davis SB, Endo A, Dicks LMT.

Arch Microbiol 201 2019年12月

記述言語：英語掲載種別：研究論文（学術雑誌）

バイオエタノール生産の原料である糖液製造過程において、微生物汚染の原因菌の一種であるBacillus属細菌の効果的な同定法を構築した。

Phylogenetic Analyses of pheS, dnaA and atpA Genes for Identification of Weissella confusa and Weissella cibaria Isolated from a South African Sugarcane Processing Factory 査読あり

Nel S, Davis SB, Endo A, Dicks LMT.

Curr Microbiol 76 2019年10月

記述言語：英語掲載種別：研究論文（学術雑誌）

バイオエタノール生産の原料である糖液製造過程において、微生物汚染の原因菌の一種であるWeissella属細菌の効果的な同定法を構築した。

Characterization of fructooligosaccharide-degrading enzymes in human commensal Bifidobacterium longum and Anaerostipes caccae 査読あり

Tanno H, Fujii T, Ose R, Hirano K, Tochio T, Endo A.

Biochem Biophys Res Commun 15 2019年10月

記述言語：英語掲載種別：研究論文（学術雑誌）

ビフィズス菌および酪酸産生菌のフルクトオリゴ糖代謝能をゲノム面及び遺伝子発現解析により考察した

Pseudofructophilic Leuconostoc citreum strain F192-5, isolated from satsuma mandarin peel. 査読あり

Maeno S, Tanizawa Y, Kajikawa A, Kanesaki Y, Kubota E, Arita M, Dicks L, Endo A.

Appl Environ Microbiol. 85 2019年10月

記述言語：英語掲載種別：研究論文（学術雑誌）

菌株レベルでフルクトフィリックな特徴を獲得した乳酸菌株の生化学的およびゲノムの特徴を明らかにした

Microbial Diversity Profiling of Polysaccharide (gum)-Producing Bacteria Isolated from a South African Sugarcane Processing Factory 査読あり

Nel S, Davis SB, Endo A, Dicks LMT.

Curr Microbiol 76 2019年05月

記述言語：英語掲載種別：研究論文（学術雑誌）

バイオエタノール生産の原料となる糖液製造過程で問題となる微生物汚染の原因菌を明らかにした

Introduction of bifunctional alcohol/acetaldehyde dehydrogenase gene (adhE) in Fructobacillus fructosus settled its fructophilic characteristics 査読あり

Maeno S, Kajikawa A, Dicks L, Endo A.

Res Microbiol 170 2019年01月

記述言語：英語掲載種別：研究論文（学術雑誌）

フルクトフィリック乳酸菌の特異な性状の理由を、遺伝子組み換えを用いて明らかにした

Impact of kestose supplementation on the healthy adult microbiota in in vitro fecal batch 査読あり

Endo A, Hirano K, Ose R, Maeno S, Tochio T.

Anaerobe 52 2019年

記述言語：英語掲載種別：研究論文（学術雑誌）

腸内細菌によるオリゴ糖代謝能を、複合系微生物叢を用いて解析した

Lactobacillus paragasseri sp. nov., a sister taxon of Lactobacillus gasseri, based on whole-genome sequence analyses. 査読あり

Tanizawa Y, Tada I, Kobayashi H, Endo A, Maeno S, Toyoda A, Arita M, Nakamura Y, Sakamoto M, Ohkuma M, Tohno M.

International Journal of Systematic and Evolutionary Microbiology 68 2018年11月

記述言語：英語掲載種別：研究論文（学術雑誌）

新種の乳酸菌 L. paragasseri を提唱した

Comparative analysis of probiotic bacteria based on a new definition of core genome. 査読あり

Satti M, Tanizawa Y, Endo A, Arita M

J Bioinform Comput Biol 16 2018年06月

記述言語：英語掲載種別：研究論文（学術雑誌）

プロバイオティクスとして利用されている乳酸菌及びビフィズス菌において、それぞれのゲノム比較を行った。

Intracellular localization of sirtuin and cell length analysis of Lactobacillus paracasei suggest possible role of sirtuin in cell division and cell shape regulation 査読あり

Torres-Barredo GA, Atarashi H, Kajikawa A, Hirata A, Endo A, Nakagawa J.

Bioscience, Biotechnology and Biochemistry 82 916 - 925 2018年05月

記述言語：英語掲載種別：研究論文（学術雑誌）

乳酸菌の長寿タンパクが細胞形態に与える影響を明らかにした。

The ability of human intestinal anaerobes to metabolize different oligosaccharides: Novel means for microbiota modulation? 査読あり

Ose R, Hirano K, Maeno S, Nakagawa J, Salminen S, Tochio T, Endo A.

Anaerobe 51 110 - 119 2018年05月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

腸内細菌のオリゴ糖代謝能について明らかにした。

In vitro and in silico characterisation of Lactobacillus paraplantarum D2-1, a starter culture for soymilk fermentation 査読あり

Endo A, Sasaki F, Maeno S, Kanesaki Y, Hamaguchi Y, Torres GA, Tomita S, Nakagawa J.

Internation Journal of Food Science and Nutrition 10 1 - 13 2018年01月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

豆乳発酵製造のための乳酸菌スターターを選抜し、その乳酸菌の発酵特性および機能性を明らかにした。

A cross-sectional comparative study of gut bacterial community of Indian and Finnish children 査読あり

Kumbhare SV, Kumar H, Chowdhury SP, Dhotre DP, Endo A, Mättö J, Ouwehand AC, Rautava S, Joshi R, Patil NP, Patil RH, Isolauri E, Bavdekar AR, Salminen S, Shouche YS.

Scientific Reports 5 10555 2017年09月

記述言語：英語掲載種別：研究論文（学術雑誌）

フィンランドとインドの小児の腸内フローラと遺伝型を解析し、遺伝型と腸内フローラの関係及び二国間の腸内フローラの違いを明らかにした。

Post-harvest biodeterioration of sugarcane: Taxonomic history and current perspectives 査読あり

Nel S, Davis SB, Endo A, Dicks L

International Sugar Journal 8 0 - 0 2017年08月

記述言語：英語掲載種別：研究論文（学術雑誌）

サトウキビ収穫後の品質低下を招く腐敗菌の分類について明らかにした。

Lactobacillus apinorum belongs to the fructophilic lactic acid bacteria 査読あり

Maeno S., Dicks L, Nakagawa J, Endo A.

Bioscience of Microbiota, Food and Health 36 147 - 149 2017年04月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

ミツバチ由来乳酸菌の非典型的な特徴を明らかにした。

Revealing the genomic differences between two subgroups in Lactobacillus gasseri 査読あり

Tada I, Tanizawa Y, Endo A, Tohno M, Arita M.

Bioscience of Microbiota, Food and Health 36 155 - 159 2017年04月

記述言語：英語掲載種別：研究論文（学術雑誌）

産業重要乳酸菌種の遺伝的不均一性について明らかにした。

Detection and analysis of Lactobacillus paracasei penicillin-binding proteins revealed presence of cholate sensitive penicillin-binding protein 3 and elongated cell shape in one of cholate sensitive strains. 査読あり

Hattori M, Torres GA, Tanaka N, Okada S, Endo A, Nakagawa J.

Bioscience of Microbiota, Food and Health 36 65 - 72 2017年02月

記述言語：英語掲載種別：研究論文（学術雑誌）

乳酸菌の細胞壁タンパク質と胆汁酸耐性および細胞形態の関係について明らかにした

Genomic characterization of a bee symbiont fructophilic Lactobacillus kunkeei reveals its niche-specific adaptation 査読あり

Maeno S, Tanizawa Y, Kanesaki Y, Kubota E, Kumar H, Dicks L, Salminen S, Nakagawa J, Arita M, Endo A.

Systematic and Applied Microbiology 39 516 - 526 2016年12月

記述言語：英語掲載種別：研究論文（学術雑誌）

An Alteration in the Cecal Microbiota Composition by Feeding of 1-Kestose Results in a Marked Increase in the Cecal Butyrate Content in Rats 査読あり

Tochio T, Kitaura Y, Nakamura S, Sugawa C, Takahashi M, Endo A, Shimomura Y.

PLoS One 18 e0166850 2016年11月

記述言語：英語掲載種別：研究論文（学術雑誌）

Bifidobacteria inhibit the growth of Porphyromonas gingivalis but not of Streptococcus mutans in an in vitro biofilm model 査読あり

Jäsberg H, Söderling E, Endo A, Beighton D, Haukioja A.

European Journal of Oral Sciences 124 251 - 258 2016年06月

記述言語：英語掲載種別：研究論文（学術雑誌）

Variations in prebiotic oligosaccharide fermentation by intestinal lactic acid bacteria 査読あり

Endo A, Nakamura S, Konishi K, Nakagawa J, Tochio T.

International Journal of Food Science and Nutrition 67 125 - 132 2016年03月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

Identification of sirtuin and its target as the ribosomal protein S4 in Lactobacillus paracasei 査読あり

Atarashi H, Kawasaki S, Niimura Y, Tanaka N, Okada S, Shiwa Y, Endo A, Nakagawa J.

Journal of General and Applied Microbiology 62 98 - 105 2016年02月

記述言語：英語掲載種別：研究論文（学術雑誌）

Early Gut Colonization with Lactobacilli and Staphylococcus in Infants: the Hygiene Hypothesis Extended 査読あり

Salminen S, Endo A, Isolauri E, Scalabrin D.

Journal of Pediatric Gastroenterology and Nutrition 62 80 - 86 2016年01月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

Comparative genomics of Fructobacillus spp. and Leuconostoc spp. reveals niche-specific evolution of Fructobacillus spp. 査読あり

Endo A, Tanizawa Y, Tanaka N, Maeno S, Kumar H, Shiwa Y, Okada S, Yoshikawa H, Dicks L, Nakagawa J, Arita M.

BMC Genomics 2015年12月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

Furry pets modulate gut microbiota composition in infants at risk for allergic disease 査読あり

Nermes M, Endo A, Aarnio J, Salminen S, Isolauri E.

Journal of Allergy and Clinical Immunology 2015年12月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

Distinctive Intestinal Lactobacillus Communities in Six-Month-Old Infants From Rural Malawi and South-Western Finland 査読あり

Aakko J, Endo A, Mangani C, Maleta K, Ashorn P, Isolauri E, Salminen S.

Journal of Pediatric Gastroenterology and Nutrition 2015年12月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

Microbiota and probiotics in canine and feline welfare 査読あり

Grześkowiak L, Endo A, Beasley S, Salminen S.

Microbiota and probiotics in canine and feline welfare 2015年08月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

Comparison of homo- and heterofermentative lactic acid bacteria for implementation of fermented wheat bran in bread 査読あり

Prückler M, Lorenz C, Endo A, Kraler M, Dürrschmid K, Hendriks K, Soares da Silva F, Auterith E, Kneifel W, Michlmayr H.

Food Microbiology 2015年08月

記述言語：英語掲載種別：研究論文（学術雑誌）

Genome sequence of three strains of Lactobacillus paracasei of different origins 査読あり

Shiwa Y, Atarahi H, Tanaka N, Okada S, Yoshikawa H, Endo A, Miyaji T, Nakagawa J.

Genome Announcement 2015年04月

記述言語：英語掲載種別：研究論文（学術雑誌）

Detection and genomic characterization of motility in Lactobacillus curvatus: confirmation of motility in a species outside the Lactobacillus salivarius clade 査読あり

Cousin FJ, Lynch SM, Harris HMB, McCann A, Lynch DB, Neville AB, Irisawa T, Okada S, Endo A, O’Toole PW.

Applied and Envinonmental Microbiology 2015年02月

記述言語：英語掲載種別：研究論文（学術雑誌）

Long-term monitoring of the human intestinal microbiota from the 2nd week to 13 years of age 査読あり

Endo A, Pärtty A, Kalliomäki M, Isolauri E, Salminen S.

Anaerobe 2014年08月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

Photorhabdus heterorhabditis sp. nov., a symbiont of the entomopathogenic nematode Heterorhabditis zealandica 査読あり

Ferreira T, van Reenen CA, Endo A, Tailliez P, Pagès S, Spröer C, Malan AP, Dicks LM.

International Journal of Systematic and Evolutionary Microbiology 2014年05月

記述言語：英語掲載種別：研究論文（学術雑誌）

Food matrices and cell conditions influence survival of Lactobacillus rhamnosus GG under heat stresses and during storage

Endo A, Teräsjärvi J, Salminen S.

International Journal of Food Microbiology 2014年05月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

Recommended minimal standards for description of new taxa of the genera Bifidobacterium, Lactobacillus and related genera 査読あり

Mattarelli P, Holzapfel W, Franz CM, Endo A, Felis GE, Hammes W, Pot B, Dicks L, Dellaglio F.

International Journal of Systematic and Evolutionary Microbiology 2014年04月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

Fructophilic characteristics of Fructobacillus spp. may be due to the absence of an alcohol/acetaldehyde dehydrogenase gene (adhE) 査読あり

Endo A, Tanaka N, Oikawa Y, Okada S, Dicks L.

Current Microbiology 2014年04月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

Presence of human enteric viruses in the stools of healthy Malawian 6 months-old infants 査読あり

Rodríguez-Díaz J., Mira-Pascual L, Collado MC, Endo A., Hyöty H, Mangani C, Maleta K, Ashorn P, Salminen S.

Journal of Pediatric Gastroenterology and Nutrition 2014年04月

記述言語：英語掲載種別：研究論文（学術雑誌）

Honeybees and beehives are rich sources for fructophilic lactic acid bacteria 査読あり

Endo, A. & Salminen, S.

Systematics and Applied Microbiology 2013年09月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

ミツバチとその巣からフルクトフィリック乳酸菌を分離し、その分離菌株のハチ幼虫病原菌への抗菌活性を調べた。

Description of Xenorhabdus khoisanae sp. nov., the symbiont of the entomopathogenic nematode Steinernema khoisanae 査読あり

Ferreira T, van Reenen CA, Endo A, Spröer C, Malan AP & Dicks LM.

International Journal of Systematic and Evolutionary Microbiology 63 3220 - 3224 2013年09月

記述言語：英語掲載種別：研究論文（学術雑誌）

線虫共生細菌である Xenorhabdus 属細菌の新菌種を分離し、Xenorhabdus khoisanae と提唱した。

The effect of growth media and physical treatments on the adhesion properties of canine probiotics. 査読あり

Grześkowiak L, Endo A, Collado MC, Pelliniemi LJ, Beasley S, Salminen S.

Journal of Applied Microbiology 2013年08月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

プロバイオティクス菌株の培養条件及び殺菌処理が粘膜への定着に及ぼす影響について検討を行った。

Lactobacillus faecis sp. nov., isolated from animal faeces. 査読あり

Endo A, Irisawa T, Futagawa-Endo Y, Salminen S, Ohkuma M & Dicks L.

International Journal of Systematic and Evolutionary Microbiology 2013年

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

動物糞便から分離した乳酸菌が新規乳酸菌であることを見出し、Lactobacillus faecis として提唱した。

Fructophilic characteristics of Fructobacillus spp. may be due to the absence of an alcohol/acetaldehyde dehydrogenase gene (adhE) 査読あり

Endo A, Tanaka N, Oikawa Y, Okada S & Dicks L.

Current Microbiology 2013年

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

Fructobacillus 属の特異な特徴が adhE 遺伝子の欠損によるものであることを示唆した。

Presence of human enteric viruses in the stools of healthy Malawian 6 months-old infants 査読あり

Rodríguez-Díaz J., Mira-Pascual L, Collado MC, Endo A., Hyöty H, Mangani C, Maleta K, Ashorn P & Salminen S.

Journal of Pediatric Gastroenterology and Nutrition 2013年

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

アフリカの国マラウィの6か月齢の乳幼児の糞便から腸管系ウィルスの検出し、検出されたウィルスの同定を行った。

Evaluation of strain-specific primers for identification of Lactobacillus rhamnosus GG 査読あり

Endo, A., Aakko, J. & Salminen, S.

FEMS Microbiology Letters 2012年12月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

プロバイオティクス乳酸菌として世界中で最も研究され、食品利用されている菌株 GG 菌の菌株特異的同定・検出法の確立を行った。

Fructophilic Lactobacillus kunkeei and Lactobacillus brevis isolated from fresh flowers, bees and bee-hives. 査読あり

Neveling, D.P., Endo, A. & Dicks, L.M.T.

Current Microbiology 2012年11月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

花、ミツバチ、ミツバチの巣などのサンプルから fructophilic 乳酸菌を分離し、特徴づけを行った。

Compositional development of Bifidobacterium and Lactobacillus microbiota is linked with crying and fussing in early infancy. 査読あり

Pärtty, A., Kalliomäki, M., Endo, A., Salminen, S. & Isolauri, E.

PLOS One 2012年07月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

乳児疝痛と腸内細菌フローラの関係について検討し、ビフィズス菌や乳酸菌の代表菌属である Lactobacillus 属細菌が多い乳児は、乳児疝痛が少ないことを見出した。

Characterization and emended description of Lactobacillus kunkeei as a fructophilic lactic acid bacterium 査読あり

Endo, A., Irisawa, T., Futagawa-Endo, Y., Takano, K., du Toit, M., Okada, S. & Dicks, L.M.T.

International Journal of Systematic and Evolutionary Microbiology　 2012年03月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

乳酸菌の一種 Lactobacillus kunkeei を生化学的に特徴づけ、種の新たな定義として提唱した。

Bifidobacterium reuteri sp. nov., Bifidobacterium callitrichos sp. nov., Bifidobacterium saguini sp. nov., Bifidobacterium stellenboschense sp. nov. and Bifidobacterium biavatii sp. nov. isolated from faeces of common marmoset (Callithrix jacchus) and red-handed tamarin (Saguinus midas). 査読あり

Endo, A., Futagawa-Endo, Y., Schumann, P., Pukall, R. & Dicks, L.M.T.

Systematic and Applied Microbiology 2012年03月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

動物糞便から分離したビフィズス菌を分類学的に研究し、5種の新規ビフィズス菌として、命名、提唱した。

Nisin F, intraperitoneally injected, may have a stabilizing effect on the bacterial population in the gastro-intestinal tract, as determined in a preliminary study with mice as model 査読あり

van Staden, D.A., Brand, A.M., Endo, A. & Dicks, L.M.T.

Letters in Applied Microbiology 2011年08月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

乳酸菌の一種が生産する抗菌性ペプチドであるナイシンFの腹腔注射が、腸内フローラへ与える影響を検討した。

Influence of carbohydrates on the isolation of lactic acid bacteria 査読あり

Endo, A., Futagawa-Endo, Y. & Dicks, L.M.T.

Journal of Applied Microbiology 2011年04月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

乳酸菌分離法の一つである集積培養法が、分離結果に及ぼす影響について分子生物学的手法を用いて考察した。

Fructobacillus tropaeoli sp. nov., a novel fructophilic lactic acid bacterium isolated from a flower 査読あり

Endo, A., Irisawa, T., Futagawa-Endo, Y., Sonomoto, K., Itoh, K., Takano, K., Okada, S. & Dicks, L..M..T.

International Journal of Systematic and Evolutionary Microbiology 2011年04月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

花より分離した新規乳酸菌をFructobacillus tropaeoli と命名、提唱した。

Lactobacillus plantarum 24, isolated from the marula fruit (Scerocarya birrea), has probiotic properties and harbors genes encoding the production of three bacteriocins 査読あり

Prins, W.A., Botha, M., Botes, M., de Kwaadsteniet, M., Endo, A. & Dicks, L.M.T.

Current Microbiology 2010年12月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

南アフリカ産アルコール飲料アマルーラの発酵中の試料から乳酸菌の一種 Lactobacillus plantarum を分離し、バクテリオシンの生産性など、その有用性を多方面から解析した。

Diversity of Lactobacillus and Bifidobacterium in feces of herbivores, omnivores and carnivores 査読あり

Endo, A., Futagawa-Endo, Y. & Dicks, L.M.T.

Anaerobe 2010年12月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

動物糞便中の Lactobacillus 及び Bifidobacterium 属細菌を培養法及び分子生物学的手法により解析し、食餌と腸内フローラの関連性について検討を行った。

Lactobacillus florum sp. nov., a novel fructophilic species isolated from flowers 査読あり

Endo, A., Futagawa-Endo, Y., Sakamoto, M., Kitahara, M. & Dicks, L.M.T.

International Journal of Systematic and Evolutionary Microbiology 2010年10月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

花より分離した新規乳酸菌を Lactobacillus florum と命名、提唱した。

Isolation and characterization of fructophilic lactic acid bacteria from fructose-rich niches 査読あり

Endo, A., Futagawa-Endo, Y. & Dicks, L.M.T.

Systematic and Applied Microbiology 2009年12月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

花や果物などの果糖豊富な環境下に生息する乳酸菌はグルコースよりも果糖を好んで生育することを見出し、その特異な特徴を明らかにした。また、これらの特徴を持つ乳酸菌を fructophilic 乳酸菌として命名した。

Lactobacillus and Bifidobacterium diversity in horse feces, revealed by PCR-DGGE 査読あり

Endo, A., Futagawa-Endo, Y. & Dicks, L.M.T.

Current Microbiology 2009年12月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

南アフリカ産のサラブレッドの有用菌フローラを分子生物学的手法により解析し、日本産との相違点を明らかにした。

Sodium acetate enhances hydrogen peroxide production in Weissella cibaria 査読あり

Endo, A., Futagawa-Endo, Y., Kawasaki, S., Dicks, L.M.T., Niimura, Y. & Okada, S.

Letters in Applied Microbiology 2009年07月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

バイオプリザバティブとして注目されている過酸化水素について、Weissella cibaria が著量の過酸化水素を生産することを見出し、さらにその生産特性について検討した。

Taxonomic Status of Malolactic Bacteria in Wine and Key Characteristics to Differentiate Species 査読あり

Dicks, L. M. T. & Endo, A.

South African Journal of Enology and Viticulture 2009年06月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

ワイン醸造中の重要な発酵プロセスであるマロラクティック発酵を行う乳酸菌について、その特徴及び現在の分類状況について解説した。

Lactobacillus 属乳酸菌の分類と非典型的な特徴査読あり

Endo, A. & Dicks, L.M.T.

日本乳酸菌学会誌 2008年11月

担当区分：筆頭著者記述言語：日本語掲載種別：研究論文（学術雑誌）

乳酸菌の代表菌属である Lactobacillus 属の現在の分類状況と、幾つかの菌種だけが持つ非典型的な特徴について解説した。

Reclassification of the genus Leuconostoc, and proposals of Fructobacillus fructosus gen. nov., comb. nov., Fructobacillus durionis comb. nov., Fructobacillus ficulneus comb. nov. and Fructobacillus pseudoficulneus comb. nov. 査読あり

Endo, A. & Okada, S.

International Journal of Systematic and Evolutionary Microbiology 2008年09月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

産業有用乳酸菌である Leuconostoc 属細菌を分類学的に研究し、属内に特異な特徴を持つ菌群を見出した。さらにそれらの菌群を新属 Fructobacillus 属に再分類することを提唱した

Monitoring the bacterial community during fermentation of sunki, an unsalted, fermented vegetable traditional to the Kiso area of Japan 査読あり

Endo, A., Mizuno, H. & Okada, S.

Letters in Applied Microbiology 2008年09月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

木曽地方の伝統的無塩漬物すんきの細菌フローラを培養法、分子遺伝学的手法により解析した。

Lactobacillus equigenerosi sp. nov., a novel coccoid Lactobacillus species isolated from faeces of thoroughbred racing horses 査読あり

Endo, A., Roos, S., Satoh, E., Morita, H., & Okada, S.

International Journal of Systematic and Evolutionary Microbiology 2008年04月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

サラブレッド腸内から分離した新規乳酸菌を Lactobacillus equigenerosi として命名、提唱した。

Lactobacillus hayakitensis sp. nov., isolated from intestines of healthy thoroughbreds 査読あり

Morita, H., Shiratori, C., Murakami, M., Takami, H., Kato, Y., Endo, A., Nakajima, F., Takagi, M., Akita, H., Okada, S., Masaoka, T.

International Journal of Systematic and Evolutionary Microbiology 2007年12月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

サラブレッド腸内から分離した新規乳酸菌を Lactobacillus hayakitensis として命名、提唱した。

Molecular profiling of Lactobacillus, Streptococcus, and Bifidobacterium species in feces of active racehorses 査読あり

Endo, A., Okada, S. & Morita, H.

Journal of General and Applied Microbiology 2007年06月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

サラブレッド腸内の有用細菌相を分子生物学的手法により解析した。コレスポンディングオーサー

Characterization of Lactococcus garvieae isolated from radish and broccoli sprouts that exhibited a KG+ phenotype, lack of virulence and absence of a capsule 査読あり

Kawanishi, M., Yoshida, T., Kijima, M., Yagyu, K., Nakai, T., Okada, S., Endo, A., Murakami, M., Suzuki, S. & Morita, H.

Letters in Applied Microbiology 2007年05月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

生食用野菜から分離した Lactococcus garvieae を魚由来の病原性 Lactococcus garvieae 菌株と比較することで、その病原性について検討した。

Lactobacillus farraginis sp. nov. and Lactobacillus parafarraginis sp. nov., two novel heterofermentative lactobacilli isolated from a compost of distilled shochu residue 査読あり

Endo, A. & Okada, S

International Journal of Systematic and Evolutionary Microbiology 2007年04月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

焼酎モロミの残渣発酵液より2種の新規乳酸菌を見出し、Lactobacillus farraginis 及び Lactobacillus parafarraginis として提唱した。

Lactobacillus composti sp. nov., a novel lactic acid bacterium isolated from a compost of distilled shochu residue 査読あり

Endo, A. & Okada, S

International Journal of Systematic and Evolutionary Microbiology 2007年04月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

焼酎モロミの残渣発酵液より新規乳酸菌を見出し、Lactobacillus composti として提唱した。

Molecular monitoring of the main changes in bacterial floral diversity in the gastrointestinal tract of a Thoroughbred foal with catarrhal enteritis by using PCR-DGGE 査読あり

Morita, H., Nakajima, F., Murakami, M., Endo, A., Suzuki, T., Shiratori, C., Kato, Y., Okatani, A. T., Akita, H. & Masaoka, T.

Journal of Equine Veterinary Science 2007年01月

記述言語：英語掲載種別：研究論文（学術雑誌）

出血性腸炎により死亡した子馬の腸内微生物相を分子生物学的手法により解析し、原因菌を特定した。

Oenococcus kitaharae sp. nov., a non-acidophilic and non-malolactic-fermenting oenococcus isolated from a composting distilled shochu residue 査読あり

Endo, A. & Okada, S.

International Journal of Systematic and Evolutionary Microbiology 2006年10月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

焼酎モロミの残渣発酵液より新規乳酸菌を見出し、Oenococcus kitaharae として提唱した。

Lactobacillus durianis Leisner et al. 2002 is a later heterotypic synonym of Lactobacillus vaccinostercus Kozaki and Okada 1983 査読あり

Dellaglio, F., Vancanneyt, M., Endo, A., Vandamme, P., Felis, G.E., Castioni, A., Fujimoto, J., Watanabe, K., & Okada, S.

International Journal of Systematic and Evolutionary Microbiology 2006年08月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

四国地方の発酵茶碁石茶から見出された乳酸菌 L. durianis が既知の L. vaccinostercus と同一菌種であることを見出し、報告した。

焼酎モロミに生息する乳酸菌に関する研究（東京農業大学博士論文）

遠藤明仁

2005年03月

記述言語：日本語掲載種別：学位論文（その他）

それまで全く知られていなかった焼酎モロミ中の乳酸菌相を培養法、分子生物学的手法により解析し、乳酸菌の存在を明らかにした。さらに芋、米、麦などの原料の違いが乳酸菌相に与える影響について検討した。

Monitoring the lactic acid bacterial diversity during shochu fermentation by PCR-denaturing gradient gel electrophoresis 査読あり

Endo, A. & Okada, S.

Journal of Bioscience and Bioengineering 2005年03月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

焼酎モロミに生息する乳酸菌を分子生物学的手法および培養法により解析した。コレスポンディングオーサー

Lactobacillus satsumensis sp. nov., isolated from mashes of shochu, a traditional Japanese distilled spirit made from fermented rice and other starchy materials. 査読あり

Endo, A. & Okada, S.

International Journal of Systematic and Evolutionary Microbiology 2005年01月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

焼酎モロミより新規乳酸菌を見出し、 Lactobacillus satsumensis として提唱した。

カイワレダイコン由来乳酸菌Lactococcus lactis による大腸菌 O157:H7 および大腸菌群の排除査読あり

奥田俊郎, 中村真理, 内田普紀, 遠藤明仁, 岡田早苗

防菌防黴誌 2002年07月

記述言語：日本語掲載種別：研究論文（学術雑誌）

乳酸菌を利用したバイオプリザベーション法により、カイワレダイコンの食中毒菌汚染排除について検討した。

乳酸菌による大腸菌群細菌生育阻害機構の解明（東京農業大学修士論文）

遠藤明仁

2002年03月

記述言語：日本語掲載種別：学位論文（その他）

乳酸菌を用いた生食用野菜バイオプリザベーション法の開発のため、乳酸菌の大腸菌群細菌生育阻害機構を検討した。

Faecalibacterium hominis Liu et al. 2023 is a later heterotypic synonym of Faecalibacterium duncaniae Sakamoto et al. 2022. 査読あり

Sakamoto M, Sakurai N, Tanno H, Iino T, Ohkuma M, Endo A.

Int J Syst Evol Microbiol 73 (8) 2023年08月

担当区分：最終著者,　責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

Faecalibacterium 属の分類学的研究結果を報告した

Spore-forming properties and enhanced oxygen tolerance of butyrate-producing Anaerostipes spp. 査読あり

Kadowaki R, Tanno H, Maeno S, Endo A.

Anaerobe. 82 102752 2023年07月

担当区分：最終著者,　責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

Anaerostipes の芽胞形成能について報告した

New gene markers for classification and quantification of Faecalibacterium spp. in the human gut 査読あり国際共著

Tanno H, Chatel JM, Martin R, Mariat D, Sakamoto M, Yamazaki M, Salminen S, Gueimonde M, Endo A.

FEMS Microbiol Ecol 99 fiad035 2023年04月

担当区分：最終著者,　責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

Faecalibacterium 分類と定量のためのマーカー遺伝子について報告した

Ribotype-dependent growth inhibition and promotion by erythritol in Cutibacterium acnes. 査読あり

Fujii T, Tochio T, Endo A.

J Cosmet Dermatol 21 5049 - 5057 2022年10月

担当区分：最終著者記述言語：英語掲載種別：研究論文（学術雑誌）

エリスリトールが特定の遺伝型のアクネ菌の生育を抑制することを明らかにした

Extracellular fructooligosaccharide degradation in Anaerostipes hadrus for co-metabolism with non-fructooligosaccharide utilizers. 査読あり

Endo A, Tanno H, Kadowaki R, Fujii T, Tochio T.

Biochem Biophys Res Commun 12 81 - 86 2022年07月

担当区分：筆頭著者,　責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

酪酸産生菌 A. hadrus の分泌型フルクトオリゴ糖分解酵素について解析した

Sakamoto M, Sakurai N, Tanno H, Iino T, Ohkuma M, Endo A.

Int J Syst Evol Microbiol. 72 （4） 2022年04月

担当区分：最終著者,　責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

Faecalibacterium 属の新種3菌種を提唱した

Gut Microbiome Characteristics in feral and domesticated horses from different geographic locations 査読あり国際共著

Ang L, Vinderola G, Endo A, Kantanen J, Jingfeng C, Binetti A, Burns P, Qingmiao S, Suying D, Zujiang Y, Rios-Covian D, Mantziari A, Beasley S, Gomez-Gallego C, Gueimonde M, Salminen S.

Commun Biol. 25 172 2022年02月

記述言語：英語掲載種別：研究論文（学術雑誌）

野生の馬と飼育下の馬の腸内マイクロバイオータの違いについて明らかにした

Are fructophilic lactic acid bacteria (FLAB) beneficial to humans? 査読あり国際共著

Dicks L, Endo A.

Beneficla Micriobes 11 3 - 11 2022年02月

担当区分：最終著者記述言語：英語掲載種別：研究論文（学術雑誌）

FLAB の機能性について解説した

16S rRNA gene sequence diversity in Faecalibacterium prausnitzii-complex taxa has marked impacts on quantitative analysis. 査読あり国際共著

Tanno H, Maeno S, Salminen S, Gueimonde M, Endo A.

FEMS Microbiol Ecol. 98 fiac004 2022年02月

担当区分：最終著者,　責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

Faecalibacterium の16S rRNA 遺伝子の多様性とそれがもたらす定量性研究へのインパクトを明らかにした

　前のページ - 次のページ　

<遠藤 明仁>

論文 - 遠藤 明仁

<遠藤　明仁>

論文 - 遠藤　明仁