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- Assistant Professor |
From Graduate School 【 display / non-display 】
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Japan Women's University Graduate School, Division of Human Living Division of Human Development Doctor Course Completed
2020.04 - 2023.03
Country：Japan
Employment Record in Research 【 display / non-display 】
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Tokyo University of Agriculture Faculty of Applied Bio-Science Department of Nutritional Science Assistant Professor
2025.03
External Career 【 display / non-display 】
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Tokyo University of Agriculture Faculty of Applied Bio-Science Department of Nutritional Science Assistant Professor
2025.04
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国立病院機構相模原病院 臨床研究センター 管理栄養士
2023.02 - 2025.03
Professional Memberships 【 display / non-display 】
Research Areas 【 display / non-display 】
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Life Science / Nutrition and health science
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Humanities & Social Sciences / Home economics, lifestyle science
Qualification and License 【 display / non-display 】
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Administrative Dietitian
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Nutritionist
Papers 【 display / non-display 】
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高脂肪食摂取時のカルシウム制限がアルカリホスファターゼ活性に及ぼす影響 Reviewed
奥裕乃, 野田聖子, 石井志穂, 山田麻子, 中岡加奈絵, 松井貞子, 五関-曽根正江
日本栄養・食糧学会誌 78 ( 4 ) 229 - 235 2025.08
Authorship：Lead author Language：Japanese Publishing type：Research paper (scientific journal)
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Effects of High-Phosphorus Intake on Bone Mineral Density in Adult Male Rats
YAMADA Asako, NODA Seiko, OKU Yuno, ISHII Shiho, NAKAOKA Kanae, GOSEKI (SONE) Masae
Journal of Home Economics of Japan 76 ( 9 ) 467 - 473 2025
Language：Japanese Publisher：The Japan Society of Home Economics
<p> Phosphorus (P) accounts for approximately 1% of body weight in living organisms and is primarily found in hard tissues, such as bones and teeth, and it is an essential element for bone mineralization. However, due to the increasing consumption of processed foods in the modern Japanese diet, excessive P intake has become a more pressing concern than P deficiency. In a previous study, we examined the short-term effects of varying dietary P levels on bone metabolism using 7-week-old male rats. In the present study, we focused on the effects of a high-phosphorus (HP) diet (1.0% P content) over a longer period and compared its impact on bone parameters in adult rats. Eleven-week-old male Sprague-Dawley rats were divided into two groups: a control diet group (Cont.; 0.3% P content) and a high-phosphorus diet group (HP; 1.0% P content), and both groups were fed their respective diets for 28 days. At the end of the experimental period, there were no significant differences in final body weight, weight gain, or food intake between the two groups. Similarly, no significant differences were observed in serum calcium or P concentrations. In the femur, no significant differences were found between the two groups in terms of bone length, bone width, bone thickness, or dry weight. However, the bone mineral density of the whole femur (including both cortical and trabecular bone) was significantly lower in the HP group than in the Cont. group. These findings indicate that prolonged intake of a high-phosphorus diet decreases femoral bone density in adult male rats and may increase the risk of fractures.</p>
DOI： 10.11428/jhej.76.467
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高脂肪食摂取時のビタミンA制限が骨評価パラメータへ及ぼす影響 Reviewed
中岡 加奈絵, 野田 聖子, 山田 麻子, 奥 裕乃, 五関 正江[曽根]
日本家政学会誌 75 ( 6 ) 247 - 255 2024.06
Language：Japanese Publisher：(一社)日本家政学会
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Calcium restriction for 28 days markedly and negatively influences bone mineral density of the femur and lumbar vertebrae regardless of the high-fat diet ingestion in young adult male rats. Reviewed International journal
Yuno Oku, Seiko Noda, Shiho Ishii, Asako Yamada, Kanae Nakaoka, Masae Goseki-Sone
Nutrition research (New York, N.Y.) 124 55 - 64 2024.04
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
Calcium (Ca) is necessary for bone calcification, and Ca deficiency leads to decreased bone mineral density (BMD). Epidemiological studies have reported a correlation between Ca intake and BMD. Although the influences of Ca deficiency on BMD have been reported, the effects of Ca restriction on bone during high-fat diet ingestion remain unclear. Therefore, we hypothesized that high-fat diet ingestion would potentiate the negative effects of Ca restriction on bone. Sprague-Dawley strain male rats (aged 11 weeks) were divided into 4 groups: basic control diet (Cont.) (11% lipid energy rate, 0.5% calcium), basic control diet with Ca restriction (CaR) (11% lipid energy rate, 0.02% calcium), high-fat diet (HF) (40% lipid energy rate, 0.5% calcium), and high-fat diet with Ca restriction (HFCaR) (40% lipid energy rate, 0.02% calcium). At 28 days after starting the experimental diets, body weights were higher in the high-fat diet groups (HF and HFCaR) than in the standard-fat diet groups (Cont. and CaR) on 2-way analysis of variance. The apparent Ca absorption rate in the Ca-restricted groups (CaR and HFCaR) was higher than in the Ca-sufficient groups (Cont. and HF). BMD and bone strength parameters of the femur and lumbar vertebrae in the Ca-restricted groups were markedly lower than in the Ca-sufficient groups, whereas there were no significant differences between the standard-fat diet and HF diet groups. These results suggest that 28 days of Ca restriction increases the risk of bone fracture and osteoporosis.
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Vitamin D restriction and/or a high-fat diet influence intestinal alkaline phosphatase activity and serum endotoxin concentration, increasing the risk of metabolic endotoxemia in rats. Reviewed International journal
Yuno Oku, Seiko Noda, Asako Yamada, Kanae Nakaoka, Masae Goseki-Sone
Nutrition research (New York, N.Y.) 112 20 - 29 2023.04
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
Vitamin D insufficiency induces calcification disorder of bone or a decrease in bone mineral density, increasing the risk of fracture. Alkaline phosphatase (ALP) activity, a differentiation marker for intestinal epithelial cells, is regulated by vitamin D. It has also been suggested that ALP may prevent metabolic endotoxemia by dephosphorylating lipopolysaccharide. We hypothesized that vitamin D restriction and/or a high-fat diet influences ALP activity in each tissue and serum lipopolysaccharide concentrations and increases the risk of metabolic endotoxemia. Eleven-week-old female rats were divided into 4 groups: basic control diet (Cont.), basic control diet with vitamin D restriction (DR), high-fat diet (HF), and high-fat diet with vitamin D restriction (DRHF) groups. They were acclimated for 28 days. The results of 2-way analysis of variance showed that intestinal ALP activity, which may contribute to an improvement in phosphate/lipid metabolism and longevity, in the high-fat diet groups (HF and DRHF) was higher than in the low-fat diet groups (Cont. and DR). ALP activity in the vitamin D-restricted groups (DR and DRHF) was lower than in the vitamin D-sufficient groups (Cont. and HF). Furthermore, serum endotoxin concentrations were significantly higher in the high-fat diet groups (HF and DRHF) than in the low-fat diet groups (Cont. and DR). In the vitamin D-restricted groups (DR and DRHF), serum endotoxin concentrations were also significantly higher than in the vitamin D-sufficient groups (Cont. and HF). These results suggest that vitamin D restriction and/or a high-fat diet increases the risk of metabolic endotoxemia.
Books and Other Publications 【 display / non-display 】
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新版食物アレルギーの栄養指導 : 食物アレルギーの栄養食事指導の手引き2022準拠
海老澤元宏, 今井孝成, 高松伸枝, 林典子, 朴善美, 奥裕乃, 他
医歯薬出版 2024.09 （ ISBN:9784263701454 ）
Total pages：ix, 189p Language：Japanese
Other Link： https://webview.isho.jp/book/detail/abs/10.32118/9784263701454
Misc 【 display / non-display 】
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Effects of Vitamin D Restriction and/or a High-fat Diet on Cyp2r1 Gene Expression in the Liver
奥裕乃, 野田聖子, 山田麻子, 中岡加奈絵, 五関(曽根)正江
日本女子大学大学院紀要 家政学研究科・人間生活学研究科 28 ( 28 ) 49 - 54 2022.03
Authorship：Lead author Language：Japanese
Other Link： https://search.jamas.or.jp/link/ui/2022265336
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野田聖子, 中岡加奈絵, 奥裕乃, 山田麻子, 田辺里枝子, 齋藤充加, 五関(曽根)正江
日本女子大学大学院紀要 家政学研究科・人間生活学研究科 28 ( 28 ) 99 - 106 2022.03
Language：Japanese
Other Link： https://search.jamas.or.jp/link/ui/2022265337
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Preparation of Baby Food at Home and Building an Emergency Stockpile of Food for Infants
中岡加奈絵, 中岡加奈絵, 野田聖子, 山田麻子, 奥裕乃, 定行まり子, 五関(曽根)正江
日本女子大学大学院紀要 家政学研究科・人間生活学研究科 28 ( 28 ) 107 - 117 2022.03
Language：Japanese
Other Link： https://search.jamas.or.jp/link/ui/2022265338
Presentations 【 display / non-display 】
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本学におけるIntegrated Clinical Nutrition Design Practicum ─自律的学習と症例検討を通じて専門職の判断力を高める PBL 型教育の実践とその効果─
松本菜々，本間和宏，若菜宣明，奥裕乃，福山直人
第14回日本栄養学教育学会学術総会 2025.09
Event date： 2025.09
Language：Japanese Presentation type：Oral presentation (general)
Venue：東京農業大学
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総合演習の成績を用いた統計学的解析による 管理栄養士国家試験合否の予測
秋山聡子，若菜宣明，奥 裕乃，本間和宏，田中越郎，福山直人
第14回日本栄養学教育学会学術総会 2025.09
Event date： 2025.09
Language：Japanese Presentation type：Oral presentation (general)
Venue：東京農業大学
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ミルクアレルゲン除去食品の官能評価
松井照明, 仲佳代, 上田由美, 岡田恵利, 奥裕乃 , 坂牧子, 朴善美, 北村勝誠, 杉浦至郎, 河合慧, 大林浩明, 坂井聡
第61回日本小児アレル ギー学会学術大会 2024.11
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高脂肪食摂取が雄または雌ラットの体組成および腰椎骨強度へ及ぼす影響
奥裕乃, 野田聖子, 山田麻子, 中岡加奈絵, 五関-曽根正江
第76回 日本栄養・食糧学会大会 2022.06
Event date： 2022.06
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家庭での離乳食づくりの実態ならびに離乳期の子ども向けの非常食の備蓄状況
中岡加奈絵, 野田聖子, 山田麻子, 奥裕乃, 定行まり子, 五関-曽根正江
第68回 日本栄養改善学会学術総会 2021.10
Event date： 2021.10
Teaching Experience 【 display / non-display 】
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子どもの食と栄養
2025.09 Institution：Japan Women's University
Level：Undergraduate (specialized)
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臨床栄養学各論(二)
2025.04 Institution：Tokyo University of Agriculture
Level：Undergraduate (specialized) Country：Japan
Social Activities 【 display / non-display 】
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食物アレルギーの栄養指導
Role(s)： Lecturer
日本アレルギー学会 総合アレルギー講習会 神戸コンベンションセンター 2025.03
Type：Seminar, workshop
食物アレルギーの栄養指導に関しての実演・講義
を医師、栄養士向けに実施した。 -
食物アレルギーの栄養指導
Role(s)： Lecturer
日本アレルギー学会 総合アレルギー講習会 パシフィコ横浜 2024.03
Type：Seminar, workshop
食物アレルギーの栄養指導に関しての実演・講義
を医師、栄養士向けに実施した。