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MIYASHITA Shin-Ichiro Assistant Professor |
Employment Record in Research 【 display / non-display 】
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Tokyo University of Agriculture Faculty of Bio-Industry Department of Food, Aroma and Cosmetic Chemistry Assistant Professor
2020.04
External Career 【 display / non-display 】
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Boston Children’s Hospital, Harvard Medical School Department of Urology at Boston Children’s Hospital, Department of Surgery and Department of Microbiology at Harvard Medical School Postdoctoral fellow
2016.01 - 2020.03
Country：United States
Research Areas 【 display / non-display 】
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Life Science / Molecular biology
Papers 【 display / non-display 】
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Delivery of single-domain antibodies into neurons using a chimeric toxin–based platform is therapeutic in mouse models of botulism Reviewed
Shin-Ichiro Miyashita, Jie Zhang, Sicai Zhang, Charles B. Shoemaker, Min Dong
Science Translational Medicine 13 ( 575 ) 2021.01
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
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Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium
Cell Host & Microbe 23 ( 2 ) 167 - 176 2018.02
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Identification and characterization of a novel botulinum neurotoxin
Nature communications 2017.08
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“Non-Toxic” Proteins of the Botulinum Toxin Complex Exert In-vivo Toxicity Reviewed
Shin-Ichiro Miyashita, Yoshimasa Sagane, Tomonori Suzuki, Takashi Matsumoto, Koichi Niwa, Toshihiro Watanabe
Scientific Reports 6 ( 31043 ) 2016.08
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1038/srep31043
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Transport of the botulinum neurotoxin–associating protein, nontoxic nonhemagglutinin, across the rat small intestinal epithelial cell monolayer
FEMS Microbiology letters 346 ( 1 ) 73 - 80 2013.10
Authorship：Lead author
Industrial Property Rights 【 display / non-display 】
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Catalytically inactive botulinum neurotoxin-like toxins and uses thereof
Min Dong, Shin-Ichiro Miyashita
Applicant：Childrens Medical Center Corp
Announcement no：US20220220466A1
Scientific Research Funds Acquisition Results 【 display / non-display 】
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神経細胞へ侵入する細菌毒素を利用した病原タンパク質分解技術の開発
Grant number：22K18198 2022.04 - 2025.03
若手研究
Authorship：Principal investigator
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ボツリヌス神経毒素を用いた神経細胞特異的な薬物送達システムの開発 研究課題
Grant number：20K22722 2020.09 - 2022.03
研究活動スタート支援
宮下 慎一郎
Authorship：Principal investigator
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経口毒性が強化された変異型ボツリヌス毒素複合体の機能解析
Grant number：22K07057 2022.04 - 2025.03
基盤研究(C)
Authorship：Coinvestigator(s)