Updated on 2023/02/21

写真b

Sugita-Konishi Yoshiko

Professor

Title

Professor

Laboratory Address

1-1-1 Sakuragaoka, Setagaya-ku , Tokyo, Japan

Laboratory Phone number

+81-3-5477-2305

External Link

Degree 【 display / non-display

  • 農学博士 ( 1983.03   東京大学 )

Employment Record in Research 【 display / non-display

  • Tokyo University of Agriculture   Faculty of Applied Bio-Science   Department of Nutritional Science   Professor

    2020.04

Professional Memberships 【 display / non-display

  • 日本食品衛生学会

    1988.04

  • Society of Toxicology

    1990.04

  • 日本食品微生物学会

    2002.04

  • 日本マイコトキシン学会

    1985.04

  • 日本農芸化学会

    1979.04

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Research Areas 【 display / non-display

  • Humanities & Social Sciences / Family and consumer sciences, and culture and living  / 食品科学

Research Interests 【 display / non-display

  • 食品微生物

  • 食の安全性,リスク評価

Papers 【 display / non-display

  • Electrophysiological Effect of Citreoviridin on Human InducedPluripotent Stem Cell-derived Cardiomyocytes

    Uchiyama Yosuke, Yamazaki Daiju, Kobayashi Naoki, Kanda Yasunari, Sugita-Konishi Yoshiko

    Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi)   63 ( 6 )   210 - 217   2022.12

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    Language:Japanese   Publisher:Japanese Society for Food Hygiene and Safety  

    <p>Citreoviridin (CTV) is a mycotoxin produced by various fungi, including <i>Penicillium citreonigrum</i>. One of the toxicities reportedly associated with CTV is neurotoxicity. CTV is also suspected to be associated with acute cardiac beriberi (also known as “Shoshin-kakke”) and Keshan disease, which can have adverse effects on the heart, so the <i>in vivo</i> and <i>in vitro</i> toxicity of CTV on the heart or cardiomyocytes in experimental animal models have been reported. However, the toxicity of CTV for the human heart, especially its electrophysiological effect, remains poorly understood. Therefore, to investigate the electrophysiological effect of CTV on the human cardiomyocytes, we conducted a multi-electrode array (MEA) using human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). The MEA revealed that 30 μmol/L of CTV stopped the beating of hiPSC-CMs, and the field potential duration and first peak amplitude were shortened at 10 μmol/L. Before the hiPSC-CMs stopped beating, the length of the inter-spike interval varied two- to four-fold. These results demonstrated that CTV induced an electrophysiological disturbance on human cardiomyocytes. This is first paper to elucidate the electrophysiological effect of CTV on human heart directly and may aid in analyzing the risk associated with CTV to ensure food safety.</p>

    DOI: 10.3358/shokueishi.63.210

    PubMed

  • Analytical Studies on Ciguateric Fish in Okinawa, Japan (II): The Grouper Variola albimarginata Reviewed

    2023.01

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.3390/jmse11020242

  • The Patrol Yeast: A new biosensor armed with antibody-receptor chimera detecting a range of toxic substances associated with food poisoning. Biosens Bioelectron Reviewed International coauthorship International journal

    Jiulong Su , Bo Zhu , Akihito Inoue , Hiroyuki Oyama , Izumi Morita 3, Jinhua Dong 4 Takanobu Yasuda 1, Yoshiko Sugita-Konishi 5, Tetsuya Kitaguchi , Norihiro Kobayashi , Shiro Miyake , Hiroshi Ueda

    Biosens Bioelectron   Oct 11   2022.01

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bios.2022.114793

  • Analysis of Ciguatoxins in Variola louti Captured off the Ogasawara (Bonin) Islands Reviewed

    Hiroya NAGASAWA, Kyoko KUNIYOSHI , Toshiaki TANIGAWA , Naoki KOBAYASHI , Yoshiko SUGITA-KONISHI , Hiroshi ASAKURA and Naomasa OSHIRO

    Food Hygiene and Safety Science   62 ( 5 )   157 - 161   2021.11

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • In vivo and In vitro Mitigation Effects of Lactic Acid Bacteria Derived from Fresh Vegetables on Aflatoxins Reviewed

    Kenji OONAKA, Naoki KOBAYASHI1, Yosuke UCHIYAMA, Mioko HONDA , Shiro MIYAKE, and Yoshiko SUGITA-KONISHI

    Food Hyg. Saf.Sci.   62 ( 5 )   148 - 156   2021.10

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    Language:English   Publishing type:Research paper (scientific journal)  

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Books and Other Publications 【 display / non-display

  • イラストで見る HACCPシステムの要点

    小西良子、三宅司郎、大仲賢二、小林直樹、脇洋一、伊藤 武( Role: Sole author)

    幸書房  2020.12 

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    Language:Japanese   Book type:Scholarly book

  • イラストで見るHACCPシステムの要点

    小西 良子, 三宅 司郎, 脇 洋平, 大仲 賢二, 小林 直樹, 伊藤 武 (食品), イカリ消毒株式会社LC環境検査センター, 環境文化創造研究所

    幸書房  2020  ( ISBN:9784782104484

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    Language:Japanese  

    CiNii Books

Misc 【 display / non-display

  • How to communicate "Risk on Food" in Shokuiku Invited

    16 ( 1 )   3 - 13   2022.01

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (bulletin of university, research institution)  

Other research activities 【 display / non-display

  • 第116回 食品衛生学会学術講演会 実行委員長

    2020.11 - 2020.12

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    第116回 食品衛生学会学術講演会の実行委員長を務めた

Honours, Awards and Prizes 【 display / non-display

  • 日本食品衛生学会論文賞

    2022.11   (公社)日本食品衛生学会   ケーススタディ:ゆでめん製造工場におけるPDCAサイクルによる微生物の分布と汚染源の特定

    大八木 伸、森田隆行、小西良子

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    Award type:International academic award (Japan or overseas)  Country:Japan

  • 日本食品衛生学会賞

    2017.11   日本食品衛生学会   食品を汚染する真菌性および寄生虫性危害要因の検出法開発と リスク評価に関する研究

    小西良子

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    Award type:International academic award (Japan or overseas)  Country:Japan

  • 遠山椿吉賞

    2013.02   (一般財団法人東京顕微鏡院)   マイコトキシンの毒性発現機序ならびに健康リスク評価に関する研究

    小西良子

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    Award type:International academic award (Japan or overseas)  Country:Japan

  • 日本マイコトキシン学会賞

    2007.01   日本マイコトキシン学会  

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    Award type:International academic award (Japan or overseas)  Country:Japan

Scientific Research Funds Acquisition Results 【 display / non-display

  • Evaluation and application of binding ability between mycotoxin and lactic acid bacteria cell wall components using kinetic analysis.

    2022.04 - 2025.03

    Grant-in-Aid for Scientific Research  Basic Research (C)

    Yoshiko Sugita-Konishi

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    Authorship:Principal investigator 

  • 食品異物及びカビ伝播の原因となる食菌性昆虫はカビ毒産生能を亢進する

    2018.04

    科学研究費補助金  基盤研究(C)

    小西良子

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    Authorship:Principal investigator 

  • 遺伝毒性を有する食品汚染カビ毒に対するシステマティックな新規安全性確保手法の開発

    2015.04 - 2018.03

    科学研究費補助金  基盤研究(C)

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    Authorship:Principal investigator 

  • 病原因子遺伝子情報を用いたジビエの食中毒危害微生物の解析と検査法

    2012.04 - 2015.03

    科学研究費補助金  基盤研究(C)

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    Authorship:Principal investigator 

Other External Funds 【 display / non-display

  • 日本国内流通食品に検出される新興カビ毒の安全性確保に関する研究

    2019.04 - 2022.03

    厚生労働省 

    吉成知也

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    Authorship:Coinvestigator(s)  Grant type:Competitive

Past of Cooperative Research 【 display / non-display

  • 食品加工工場における微生物制御に関する研究

    2020.09

    セッツ株式会社  学内共同研究  Cooperative Research within an Affiliated University or Institute

    盛田 隆行

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    Authorship:Coinvestigator(s) 

Presentations 【 display / non-display

  • The effects of citreoviridin on human induced pluripotent stem cell–derived cardiomyocytes International coauthorship International conference

    Y.Uchiyama et al

    International Symposium of Mycotoxicology  2022.08  Japanese Society of Mycotoxicology, Thai Society of Mycotoxicology

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    Event date: 2022.08

    Language:English   Presentation type:Oral presentation (general)  

    Venue: Faculty of Veterinary Medicine, Kasetsart University   Country:Thailand  

  • 植物由来乳酸菌の加熱および酸処理によるアフラトキシン結合能への影響

    大仲 賢二、小林 直樹、豊泉 美貴、萩原喜久美、島津 徳人、三宅 司郎、小西 良子

    2022.11  日本食品衛生学会

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    Event date: 2022.11

    Language:Japanese   Presentation type:Poster presentation  

    Venue:長崎 出島メッセ  

  • Effects of environmental changes on sterigmatocystin production in Aspergillus section Versicolores International coauthorship

    Yonaha et al

    International Symposium of Mycotoxicology   2022.08  Japanese Society of Mycotoxicology, Thai Society of Mycotoxicology

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    Event date: 2022.08

    Language:English  

    Venue: Faculty of Veterinary Medicine, Kasetsart University   Country:Thailand  

  • Discovery of candidate citreoviridin biosynthesis gene cluster in Penicillium citreonigrum International coauthorship International conference

    Izawa

    International Symposium of Mycotoxicology  2022.08  Japanese Society of Mycotoxicology, Thai Society of Mycotoxicology

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    Event date: 2022.08

    Language:English   Presentation type:Oral presentation (general)  

    Venue: Faculty of Veterinary Medicine, Kasetsart University   Country:Thailand  

  • 分岐鎖アミノ酸が腸管上皮細胞に及ぼす影響 International conference

    香西 歩、岩槻 健、清水 誠、小西 良子、只石 幹、服部 一夫

    2022年度 日本農芸化学会 大会  2022.03 

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    Event date: 2022.03

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Web  

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Teaching Experience 【 display / non-display

  • 食品衛生分析学

    Institution:Azabu University

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  • 食品機能学

    Institution:J. F. Oberlin University

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  • 食品安全学

    Institution:Azabu University

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  • 食品危害学

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  • 食品加工・保蔵学

    Institution:Azabu University

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Committee Memberships 【 display / non-display

  •   President  

    2021.06   

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    Committee type:Academic society

  • 防菌防黴学会   評議委員  

    2020.06   

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    Committee type:Academic society

  • 獣医公衆衛生研究   副編集委員長  

    2020.06   

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    Committee type:Academic society

  • 日本食品微生物学会   評議委員  

    2013.01 - 2020.06   

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    Committee type:Academic society

    現在は評議員

  • 東京都   東京都食品安全情報委員  

    2012.04 - 2022.06   

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    Committee type:Municipal

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Social Activities 【 display / non-display

  • 微生物はマルチプレーヤー

    Role(s): Lecturer

    千葉県長正高校  文科省 スーパーサイエンス高校プログラム  千葉県立長生高校  2022.09

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    Audience: High school students

    Type:Lecture

    スーパーサイエンス高校に選抜されている千葉県立長生高校において、サイエンスの面白さを講義した。