Title |
Professor |
Laboratory Address |
1-1-1 Sakuragaoka, Setagaya-ku , Tokyo, Japan |
Laboratory Phone number |
+81-3-5477-2305 |
External Link |
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Sugita-Konishi Yoshiko Professor |
From Graduate School 【 display / non-display 】
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The University of Tokyo Graduate School, Division of Agricultural Science Doctor Course Completed
1978.04 - 1983.03
Country:Japan
Studying abroad experiences 【 display / non-display 】
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1989.08 - 1990.12 Leeds University
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2000.10 - 2001.01 ミシガン州立大学 客員研究員
Employment Record in Research 【 display / non-display 】
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Tokyo University of Agriculture Faculty of Applied Bio-Science Department of Nutritional Science Professor
2020.04
External Career 【 display / non-display 】
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Azabu University School of Life and Environmental Science Professor
2013.04
Professional Memberships 【 display / non-display 】
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日本食品衛生学会
1988.04
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Society of Toxicology
1990.04
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日本食品微生物学会
2002.04
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日本マイコトキシン学会
1985.04
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日本農芸化学会
1979.04
Research Areas 【 display / non-display 】
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Humanities & Social Sciences / Family and consumer sciences, and culture and living / 食品科学
Papers 【 display / non-display 】
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Uchiyama Yosuke, Yamazaki Daiju, Kobayashi Naoki, Kanda Yasunari, Sugita-Konishi Yoshiko
Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi) 63 ( 6 ) 210 - 217 2022.12
Language:Japanese Publisher:Japanese Society for Food Hygiene and Safety
<p>Citreoviridin (CTV) is a mycotoxin produced by various fungi, including <i>Penicillium citreonigrum</i>. One of the toxicities reportedly associated with CTV is neurotoxicity. CTV is also suspected to be associated with acute cardiac beriberi (also known as “Shoshin-kakke”) and Keshan disease, which can have adverse effects on the heart, so the <i>in vivo</i> and <i>in vitro</i> toxicity of CTV on the heart or cardiomyocytes in experimental animal models have been reported. However, the toxicity of CTV for the human heart, especially its electrophysiological effect, remains poorly understood. Therefore, to investigate the electrophysiological effect of CTV on the human cardiomyocytes, we conducted a multi-electrode array (MEA) using human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). The MEA revealed that 30 μmol/L of CTV stopped the beating of hiPSC-CMs, and the field potential duration and first peak amplitude were shortened at 10 μmol/L. Before the hiPSC-CMs stopped beating, the length of the inter-spike interval varied two- to four-fold. These results demonstrated that CTV induced an electrophysiological disturbance on human cardiomyocytes. This is first paper to elucidate the electrophysiological effect of CTV on human heart directly and may aid in analyzing the risk associated with CTV to ensure food safety.</p>
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Survey and risk assessment of aflatoxins and sterigmatocystin in Japanese staple food items and the evaluation of an in-house ELISA technique for rapid screening Reviewed
T.Yoshinari, Y.Sugita-Konishi, E.Sato,H.Takeuchi, M.Taniguchi,T.Fukumitsu,A.Shimoyama,,A.Nakamura,S.Murayama,S.Owaki, S.Miyake, Y.Hara-Kudo
Food Control ( 157 ) 2024.03
Language:English Publishing type:Research paper (scientific journal)
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Kobayashi Naoki, Okano Kiyoshi, Sugita-Konishi Yoshiko
Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi) 64 ( 5 ) 179 - 184 2023.10
Language:Japanese Publisher:Japanese Society for Food Hygiene and Safety
<p>Spices have been known to be highly contaminated commodities with mycotoxins. The Codex Alimentarius reports that nutmeg is particularly contaminated with aflatoxins (AFs) and ochratoxin A (OTA). To eliminate contaminated commodities, visual sorting and bright greenish-yellow fluorescence (BGYF) sorting are used as low-cost technologies in production engineering. In Indonesia, nutmeg is mainly sorted by visual sorting and classified into three grades according to the Indonesian national standards, with importers further defining their own brand as imported products. In this study, we evaluate the efficacy of BGYF sorting as a further selection method to reduce AFs and OTA using the importer’s own brand. Further, the level of these mycotoxins and the relationship between fungal flora and mycotoxin contamination were examined. These results showed that BGYF sorting effectively reduces AFs as well as OTA. In addition, BGYF-positive groups were infected by <i>Aspergillus</i> sections <i>Flavi</i>, <i>Nigri</i>, and <i>Circumdati</i>.</p>
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Analytical Studies on Ciguateric Fish in Okinawa, Japan (II): The Grouper Variola albimarginata Reviewed
2023.01
Language:English Publishing type:Research paper (scientific journal)
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The Patrol Yeast: A new biosensor armed with antibody-receptor chimera detecting a range of toxic substances associated with food poisoning. Biosens Bioelectron Reviewed International coauthorship International journal
Jiulong Su , Bo Zhu , Akihito Inoue , Hiroyuki Oyama , Izumi Morita 3, Jinhua Dong 4 Takanobu Yasuda 1, Yoshiko Sugita-Konishi 5, Tetsuya Kitaguchi , Norihiro Kobayashi , Shiro Miyake , Hiroshi Ueda
Biosens Bioelectron Oct 11 2022.01
Language:English Publishing type:Research paper (scientific journal)
Books and Other Publications 【 display / non-display 】
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イラストで見る HACCPシステムの要点
小西良子、三宅司郎、大仲賢二、小林直樹、脇洋一、伊藤 武( Role: Sole author)
幸書房 2020.12
Language:Japanese Book type:Scholarly book
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小西 良子, 三宅 司郎, 脇 洋平, 大仲 賢二, 小林 直樹, 伊藤 武 (食品), イカリ消毒株式会社LC環境検査センター, 環境文化創造研究所
幸書房 2020 ( ISBN:9784782104484 )
Language:Japanese
Misc 【 display / non-display 】
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How to communicate "Risk on Food" in Shokuiku Invited
16 ( 1 ) 3 - 13 2022.01
Authorship:Lead author Language:Japanese Publishing type:Article, review, commentary, editorial, etc. (bulletin of university, research institution)
Other research activities 【 display / non-display 】
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第116回 食品衛生学会学術講演会 実行委員長
2020.11 - 2020.12
第116回 食品衛生学会学術講演会の実行委員長を務めた
Honours, Awards and Prizes 【 display / non-display 】
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日本食品衛生学会論文賞
2022.11 (公社)日本食品衛生学会 ケーススタディ:ゆでめん製造工場におけるPDCAサイクルによる微生物の分布と汚染源の特定
大八木 伸、森田隆行、小西良子
Award type:International academic award (Japan or overseas) Country:Japan
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日本食品衛生学会賞
2017.11 日本食品衛生学会 食品を汚染する真菌性および寄生虫性危害要因の検出法開発と リスク評価に関する研究
小西良子
Award type:International academic award (Japan or overseas) Country:Japan
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遠山椿吉賞
2013.02 (一般財団法人東京顕微鏡院) マイコトキシンの毒性発現機序ならびに健康リスク評価に関する研究
小西良子
Award type:International academic award (Japan or overseas) Country:Japan
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日本マイコトキシン学会賞
2007.01 日本マイコトキシン学会
Award type:International academic award (Japan or overseas) Country:Japan
Scientific Research Funds Acquisition Results 【 display / non-display 】
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Evaluation and application of binding ability between mycotoxin and lactic acid bacteria cell wall components using kinetic analysis.
2022.04 - 2025.03
Grant-in-Aid for Scientific Research Basic Research (C)
Yoshiko Sugita-Konishi
Authorship:Principal investigator
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食品異物及びカビ伝播の原因となる食菌性昆虫はカビ毒産生能を亢進する
2018.04
科学研究費補助金 基盤研究(C)
小西良子
Authorship:Principal investigator
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遺伝毒性を有する食品汚染カビ毒に対するシステマティックな新規安全性確保手法の開発
2015.04 - 2018.03
科学研究費補助金 基盤研究(C)
Authorship:Principal investigator
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病原因子遺伝子情報を用いたジビエの食中毒危害微生物の解析と検査法
2012.04 - 2015.03
科学研究費補助金 基盤研究(C)
Authorship:Principal investigator
Other External Funds 【 display / non-display 】
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日本国内流通食品に検出される新興カビ毒の安全性確保に関する研究
2019.04 - 2022.03
厚生労働省
吉成知也
Authorship:Coinvestigator(s) Grant type:Competitive
Past of Cooperative Research 【 display / non-display 】
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食品加工工場における微生物制御に関する研究
2020.09
セッツ株式会社 学内共同研究 Cooperative Research within an Affiliated University or Institute
盛田 隆行
Authorship:Coinvestigator(s)
Presentations 【 display / non-display 】
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The effects of citreoviridin on human induced pluripotent stem cell–derived cardiomyocytes International coauthorship International conference
Y.Uchiyama et al
International Symposium of Mycotoxicology 2022.08 Japanese Society of Mycotoxicology, Thai Society of Mycotoxicology
Event date: 2022.08
Language:English Presentation type:Oral presentation (general)
Venue: Faculty of Veterinary Medicine, Kasetsart University Country:Thailand
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植物由来乳酸菌の加熱および酸処理によるアフラトキシン結合能への影響
大仲 賢二、小林 直樹、豊泉 美貴、萩原喜久美、島津 徳人、三宅 司郎、小西 良子
2022.11 日本食品衛生学会
Event date: 2022.11
Language:Japanese Presentation type:Poster presentation
Venue:長崎 出島メッセ
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Effects of environmental changes on sterigmatocystin production in Aspergillus section Versicolores International coauthorship
Yonaha et al
International Symposium of Mycotoxicology 2022.08 Japanese Society of Mycotoxicology, Thai Society of Mycotoxicology
Event date: 2022.08
Language:English
Venue: Faculty of Veterinary Medicine, Kasetsart University Country:Thailand
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Discovery of candidate citreoviridin biosynthesis gene cluster in Penicillium citreonigrum International coauthorship International conference
Izawa
International Symposium of Mycotoxicology 2022.08 Japanese Society of Mycotoxicology, Thai Society of Mycotoxicology
Event date: 2022.08
Language:English Presentation type:Oral presentation (general)
Venue: Faculty of Veterinary Medicine, Kasetsart University Country:Thailand
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分岐鎖アミノ酸が腸管上皮細胞に及ぼす影響 International conference
香西 歩、岩槻 健、清水 誠、小西 良子、只石 幹、服部 一夫
2022年度 日本農芸化学会 大会 2022.03
Event date: 2022.03
Language:English Presentation type:Oral presentation (general)
Venue:Web
Teaching Experience 【 display / non-display 】
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食品危害学
Committee Memberships 【 display / non-display 】
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President
2021.06
Committee type:Academic society
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防菌防黴学会 評議委員
2020.06
Committee type:Academic society
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獣医公衆衛生研究 副編集委員長
2020.06
Committee type:Academic society
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日本食品微生物学会 評議委員
2013.01 - 2020.06
Committee type:Academic society
現在は評議員
Social Activities 【 display / non-display 】
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微生物はマルチプレーヤー
Role(s): Lecturer
千葉県長正高校 文科省 スーパーサイエンス高校プログラム 千葉県立長生高校 2022.09
Audience: High school students
Type:Lecture
スーパーサイエンス高校に選抜されている千葉県立長生高校において、サイエンスの面白さを講義した。