Updated on 2022/12/06

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SAITO Akihiro

Assistant Professor

Title

Assistant Professor

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From Graduate School 【 display / non-display

  • Tokyo University of Agriculture   Graduate School, Division of Agriculture   Department of Agricultural Chemistry   Doctoral program (second term)   Completed

    - 2009.03

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    Country:Japan

Studying abroad experiences 【 display / non-display

  • 2019.04 - 2020.03   French National Institute for Agricultural Research (INRA/INRAE), BPMP(Biochimie et physiologie moléculaire des plantes), Montpellier, France   Research on iron nutrition of higher plants

Degree 【 display / non-display

  • Ph.D. (Agricultural Chemistry) ( 2009.03   Tokyo University of Agriculture )

Employment Record in Research 【 display / non-display

  • Tokyo University of Agriculture   Faculty of Applied Bio-Science   Department of Applied Biology and Chemistry   Assistant Professor

    2011.04 - 2018.03

  • Tokyo University of Agriculture   Faculty of Applied Bio-Science   Department of Agricultural Chemistry   Assistant Professor

    2018.04 - 2019.03

  • Tokyo University of Agriculture   Faculty of Applied Bio-Science   Department of Agricultural Chemistry   Invited Researcher, French National Research Institute for Agriculture, Food and Environment (INRA/INRAE) Montpellier, France

    2019.04 - 2020.03

  • Tokyo University of Agriculture   Faculty of Applied Bio-Science   Department of Agricultural Chemistry   Assistant Professor

    2020.04

External Career 【 display / non-display

  • Institut national de la recherche agronomique (INRA/INRAE)   Biochimie et physiologie moléculaire des plantes (B&PMP), Montpellier   Researcher

    2019.04 - 2020.03

  • The University of Tokyo   Graduate School of Agricultural and Life Sciences   Researcher

    2010.04 - 2011.03

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    Country:Japan

  • Waseda University   Faculty of Education and Integrated Science   Postdoctoral Fellowships of Japan Society for the Promotion of Science

    2009.10 - 2010.03

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    Country:Japan

  • The University of Tokyo   Graduate School of Frontier Sciences   Postdoctoral Fellowships of Japan Society for the Promotion of Science

    2009.04 - 2009.09

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    Country:Japan

Professional Memberships 【 display / non-display

  • Japanese Society of Soil Science and Plant Nutrition

    2004.06

  • The Japanese Society of Plant Physiologists

    2005.01

  • The Botanical Society of Japan

    2009.04

  • The Japanese Society of Photosynthesis Research

    2009.04

  • International Society of Photosynthesis Research

    2010.03

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Research Areas 【 display / non-display

  • Others / Others  / 植物栄養学・土壌学

Research Interests 【 display / non-display

  • Plant Nutrition

  • Photosynthesis

  • Chloroplast

  • Mitochondria

  • Vacuole

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Research seeds 【 display / non-display

  • 「栄養強化イネ」 品種の突然変異育種

Papers 【 display / non-display

  • N Absorption, Transport, and Recycling in Nodulated Soybean Plants by Split-Root Experiment Using 15N-Labeled Nitrate Reviewed

    Maria Doi , Kyoko Higuchi , Akihiro Saito, Takashi Sato and Takuji Ohyama

    Nitrogen   3   636 - 651   2022.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.3390/nitrogen3040042

  • A deep placement of lime nitrogen reduced the nitrate leaching and promote soybean growth and seed yield Reviewed

    Takuji Ohyama, Keisuke Ikebe, Sotaro Okuoka, Tomoya Ozawa, Takuya Nishiura, Taiga Ishiwata, Ayane Yamazaki, Fumu Tanaka, Toru Takahashi, Takumi Umezawa, Hiroyuki Ohshima, Taku Kato, Maeda Yoshiyuki, Akihiro Saito, Kyoko Higuchi, Norikuni Ohtake, Yoshihiko Takahashi, Naoki Harada, and Naoko Ohkama-Ohtsu

    Crop and Environment   in press   2022.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1016/j.crope.2022.09.002

  • Shotgun proteomic investigation of methyltransferase and methylation profiles in lipopolysaccharide stimulated RAW264.7 murine macrophages Reviewed International journal

    Yumi AIZAWA, Masaru MORI, Tsukasa SUZUKI, Akihiro SAITO, Hirofumi INOUE

    Biomedical Research   43 ( 3 )   73 - 80   2022.04

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: doi.org/10.2220/biomedres.43.73

  • “Live-Autoradiography” Technique Reveals Genetic Variation in the Rate of Fe Uptake by Barley Cultivars Reviewed International journal

    Kyoko Higuchi, Keisuke Kurita, Takuro Sakai, Nobuo Suzui, Minori Sasaki, Maya Katori, Yuna Wakabayashi, Yuta Majima, Akihiro Saito, Takuji Ohyama and Naoki Kawachi

    Plants   11 ( 6 )   817   2022.03

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/plants11060817

  • Application of nitrate, ammonium, or urea changes the concentrarions of ureides, urea, amino acids and other metabolites in xylem sap and in the organs of soyubean plants (Glycine max (L.) Merr.). Reviewed International journal

    Yuki Ono, Masashige Fukasawa, Kuni Sueyoshi, Norikuni Ohtake, Takashi Sato, Sauiri Tanabata, Ryo Toyota, Kyoko Higuchi, Akihiro Saito, Takuji Ohyama

    International Journal of Molecular Sciences   22 ( 9 )   4573   2021.06

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    Language:English   Publishing type:Research paper (scientific journal)  

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Misc 【 display / non-display

  • Elucidation of efficient photosynthesis in plants with limited iron Invited Reviewed

    Kyoko Higuchi and Akihiro Saito

    Soil Science and Plant Nutrition   2022.07

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    Authorship:Lead author   Language:English   Publishing type:Article, review, commentary, editorial, etc. (bulletin of university, research institution)  

    DOI: 10.1080/00380768.2022.2106115

Honours, Awards and Prizes 【 display / non-display

  • Poster Award (ICOBTE 2015 FUKUOKA)

    2015.07   International Conference on the Biogeochemistry of Trace Elements  

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    Award type:International academic award (Japan or overseas)  Country:Japan

  • Poster Award, JSSSPN 2013 (Nagoya University)

    2013.09   Japanese Society of Soil Science and Plant Nutrition  

    Akihiro Saito, Katsuki Kato, Tomomi Nakajima, Eitaro Miwa, Kyoko Higuchi

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    Award type:International academic award (Japan or overseas)  Country:Japan

  • Poster Award, JSSSPN 2009 (Kyoto University)

    2009.09   Japanese Society of Soil Science and Plant Nutrition  

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

Scientific Research Funds Acquisition Results 【 display / non-display

  • 可塑性に富むオオムギ光化学系の多様な鉄欠乏順応機構の解明

    2020.04 - 2023.03

    科学研究費補助金  基盤研究(B)

    樋口恭子

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    Authorship:Coinvestigator(s) 

  • 重金属過剰で誘導されるミトコンドリア選択的オートファジーの分子機構

    2016.04 - 2019.03

    科学研究費補助金  若手研究(B)

    齋藤彰宏

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    Authorship:Principal investigator 

  • 基幹的代謝の最適化に基づくオオムギの鉄欠乏適応機構の解明

    2013.04 - 2015.03

    科学研究費補助金  基盤研究(B)

    樋口恭子

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    Authorship:Coinvestigator(s) 

  • 集光機能の改良に基づく無機栄養ストレス耐性作物の創出

    2012.04 - 2014.03

    科学研究費補助金  若手研究(B)

    齋藤彰宏

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    Authorship:Principal investigator 

    鉄は葉緑体の電子伝達系の構成因子であり、安定した光合成を可能にする。仮に鉄が長期的に欠乏すると、葉緑体の電子伝達が異常となり、最終的に光酸化ストレスによって細胞死が起こる。本研究では、鉄欠乏オオムギの光合成機能の最適化を担う必須因子HvLhcb1.12に着目した。HvLhcb1.12は集光性アンテナタンパク質の一種であるが、そのN末端側には多数のリン酸化部位が存在する。本遺伝子をイネに導入した結果、過剰光条件下での収量が野生型のイネより約25%増加し、光酸化ストレスの回避に貢献することが示された。

  • オオムギ地上部に存在する新規鉄欠乏耐性機構の解明

    2008.04 - 2010.03

    科学研究費補助金  特別研究員推奨費

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    Authorship:Principal investigator 

    植物において鉄は光合成、呼吸、およびその他の酸化還元反応や代謝に必須な役割を担っている。本研究では鉄欠乏に適応したオオムギの性質に着目し、1.オオムギ体内での鉄移行システム、2.オオムギ細胞内鉄貯蔵システム、3.鉄欠乏下での光合成の維持能力という3つの観点から解析を進めた。この中で、マイクロアレイ解析を実施し、鉄欠乏耐性に関与しうる遺伝子を絞り込んだところ、クロロフィルa/b結合蛋白質をコードする遺伝子Lhcb1のホモログ遺伝子が大幅に発現上昇していることが明らかになった。そこで、鉄欠乏誘導性のLhcb1遺伝子を単離し、さらに、Lhcb1の蓄積に異常を示すオオムギ変異株を用いて解析を進めた。この結果、Lhcb1は特に鉄欠乏で発生する光ストレスの回避に必須な因子であることが明らかになった。本研究により植物の鉄栄養研究と光合成研究にまたがって新規な鉄欠乏適応機構の一端が明らかにされた。

Other External Funds 【 display / non-display

  • 良食味化・多収化を目指した「鉄栄養強化イネ」 新品種の効率的育種と高品質多収栽培法の確立

    2021.12 - 2025.03

    東京農業大学 

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    Authorship:Principal investigator  Grant type:Competitive

  • Development and practical application of a new "nutritionally enhanced rice" to improve the nutritional metabolism of modern humans - Development of a unique brand of rice from Tokyo University of Agriculture-

    2018.06 - 2020.03

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    Grant type:Competitive

  • Establishment of rice lines with the abilities to improve heavy metal contamination in soils

    2013.04 - 2015.03

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    Authorship:Principal investigator  Grant type:Competitive

Past of Commissioned Research 【 display / non-display

  • 企業の研究支援(複数)

    2018.04 - 2019.03

    一般受託研究  The General Consignment Study

Past of Cooperative Research 【 display / non-display

  • Joint research with NARO

    2017.04

    Cooperative Research within an Affiliated University or Institute  Cooperative Research within an Affiliated University or Institute

Presentations 【 display / non-display

  • 鉄高集積イネ突然変異体tetsu1の体内の遷移元素分配様式とその責任遺伝子の探索 International conference

    齋藤彰宏・小林岳央・西野俊太・中山智美・川野ななみ・大山卓爾・樋口恭子

    第67 回日本土壌肥料学会(東京大会:東京大学・東京農業大学・東京農工大学)  2022.09 

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    Event date: 2022.09

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 光合成鉄利用効率を指標としたオオムギ品種サラブ1 ×ムサシノムギQTL 解析の立ち上げ International conference

    齋藤彰宏、古幡真由子、小林岳央、久野裕、樋口恭子

    第67 回日本土壌肥料学会(東京大会:東京大学・東京農業大学・東京農工大学)  2022.09 

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    Event date: 2022.09

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 明所におけるライブオートラジオグラフィー装置を用いた葉への鉄流入速度のリアルタイム計測

    樋口恭子、栗田圭輔、酒井卓郎、鈴井伸郎、佐々木実莉、香取摩耶、若林優奈、間嶋勇太、齋藤彰宏、大山卓爾、河地有木

    第67 回日本土壌肥料学会(東京大会:東京大学・東京農業大学・東京農工大学)  2022.09 

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    Event date: 2022.09

    Language:Japanese   Presentation type:Oral presentation (general)  

  • Multiple physiological mechanisms and factors responsible for proper photosynthesis in barley under iron-deficient conditions International conference

    Akihiro Saito, Hiroshi Hisano, Takuji Ohyama, Kyoko Higuchi

    20th International Symposium on Iron Nutrition and Interactions in Plants, ISINIP2022 (Reims, France)  2022.07 

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    Event date: 2022.07

    Language:English   Presentation type:Oral presentation (general)  

  • 農大発:栄養強化玄米の150日間混餌投与投与試験における安全性試験 International conference

    井上博文、長内敬典、鈴木善温、関本 純輝、大島宏之、鈴木 司、齋藤 彰宏 、石見 佳子

    日本食生活学会第64回大会  2022.05 

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    Event date: 2022.05

    Language:English   Presentation type:Oral presentation (general)  

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Teaching Experience 【 display / non-display

  • 細胞生物学

  • 卒業論文

  • 無機化学(一)

  • 分析化学実験

  • 研究室演習(一)

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Committee Memberships 【 display / non-display

  • Japanese Society of Soil Science and Plant Nutrition   Steering Committee Member of the 68th Japanese Society of Soil Science and Plant Nutrition  

    2021.04 - 2022.09   

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    Committee type:Academic society

  • Japanese Society of Soil Science and Plant Nutrition   Management Committee for the 2018 election  

    2018.04 - 2019.03   

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    Committee type:Academic society

  • The Japanese Society of Plant Physiologists   Steering Committee Member, The 56th Annual Meeting of the Japanese Society of Plant Physiologists  

    2014.04 - 2015.03   

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    Committee type:Academic society

Social Activities 【 display / non-display

  • The 10th Seminar of the "Section of three aspects of rice as 'Ine' (cultivated rice), 'Kome' (harvested rice), and 'Gohan' (cooked rice) "

    Research Institute of Agricultural Life Science in TUA  2021.09

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    Audience: College students, Graduate students, Teachers, Researchesrs, General, Scientific, Company, Civic organization, Governmental agency, Media

    Type:Seminar, workshop

  • AGRITECH SUMMIT2021

    Role(s): Guest

    Nikkei newspaper company  2021.06 - 2021.07

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    Audience: College students, Graduate students, Teachers, Researchesrs, General, Scientific, Company, Civic organization, Governmental agency, Media

    Type:Seminar, workshop

  • Participation in the symposium on Industry-Academia-Government Collaboration Research HUB Initiative Symposium

    Role(s): Guest

    Tokyo University of Agriculture  Industry-Academia-Government Collaboration Research HUB Initiative Symposium on TUA  2020.12

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    Audience: College students, Teachers, Researchesrs, General, Scientific, Company, Civic organization, Governmental agency

    Type:Seminar, workshop

  • Report on Innovative Technology Research Results of Tokyo University of Agriculture

    Role(s): Guest, Logistic support

    2018.12

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    Audience: Researchesrs, General

    Type:Lecture

  • Research support and advisors to companies

    Role(s): Consultant, Official expert

    2018.04

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Media Coverage 【 display / non-display

  • Support Consortium for Learning for Elementary School Students

    Support Consortium for Learning for Elementary School Students  2018.04

Academic Activities 【 display / non-display

  • "Agricultural chemistry-from the beginning to the future", the museum of Tokyo University of Agriculture

    2018.09 - 2019.08

  • 110th Anniversary Kickoff Symposium on Department of Agricultural Chemistry, TUA

    2018.03

Basic stance of industry-university cooperation 【 display / non-display

  • To make our new research results available to society, we need to work with companies to promote commercialization with the cooperation of the government. I am of the position that industry-academia collaboration is critical.

Attractiveness of Research 【 display / non-display

  • 私達の生活は植物(光合成生物)によって支えられています。私たちは、不良環境でも光合成を続けられる新しい植物の提案や開発を目指し、植物の環境適応能力を幅広く調べています。植物の研究に意欲のある学生の皆さん、ぜひ一緒に研究をしましょう。