Papers - TOMIZAWA, Motohiro
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Nicotinic agonist binding site mapped by methionine- and tyrosine-scanning coupled with azidochloropyridinyl photoaffinity labeling. Reviewed
Tomizawa, M.; Talley, T. T.; Park, J. F.; Maltby, D.; Medzihradszky, K. F.; Durkin, K. A.; Cornejo-Bravo, J. M.; Burlingame, A. L.; Casida, J. E.; Taylor, P.
Journal of Medicinal Chemistry 52 3735 - 3741 2009.07
Authorship:Lead author Language:English Publishing type:Research paper (scientific journal)
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Bis-neonicotinoid insecticides: observed and predicted binding interactions with the nicotinic receptor. Reviewed
Ohno, I.; Tomizawa, M.; Durkin, K. A.; Casida, J. E.; Kagabu, S.
Bioorganic and Medicinal Chemistry Letters [Corrigendum published in the journal 19, 4886 (2009)]. 19 3449 - 3452 2009.07
Authorship:Corresponding author Language:English Publishing type:Research paper (scientific journal)
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Neonicotinoid substituents forming a water bridge at the nicotinic acetylcholine receptor. Reviewed
Ohno, I.; Tomizawa, M.; Durkin, K. A.; Casida, J. E.; Kagabu, S.
Journal of Agricultural and Food Chemistry 57 2436 - 2440 2009.03
Authorship:Corresponding author Language:English Publishing type:Research paper (scientific journal)
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Molecular features of neonicotinoid pharmacophore variants interacting with the insect nicotinic receptor. Reviewed
Ohno, I.; Tomizawa, M.; Durkin, K. A.; Naruse, Y.; Casida, J. E.; Kagabu, S.
Chemical Research in Toxicology 22 476 - 482 2009.03
Authorship:Corresponding author Language:English Publishing type:Research paper (scientific journal)
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Molecular recognition of neonicotinoid insecticides: the determinants of life or death. Reviewed
Tomizawa, M.; Casida, J. E.
Accounts of Chemical Research 42, 260-269 (2009). 2009.02
Authorship:Lead author Language:English Publishing type:Research paper (scientific journal)
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Potency and selectivity of trifluoroacetylimino and pyrazinoylimino nicotinic insecticides and their fit at a unique binding site niche. Reviewed
Tomizawa, M.; Kagabu, S.; Ohno, I.; Durkin, K. A.; Casida, J. E.
Journal of Medicinal Chemistry 51 4213 - 4218 2008.07
Authorship:Lead author Language:English Publishing type:Research paper (scientific journal)
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Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore. Reviewed
Talley, T. T.; Harel, M.; Hibbs, R. E.; Radic’, Z.; Tomizawa, M.; Casida, J. E.; Taylor, P.
Proceedings of the National Academy of Sciences of the United States of America 105 7606 - 7611 2008.05
Language:English Publishing type:Research paper (scientific journal)
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Insecticide interactions with gamma-aminobutyric acid and nicotinic receptors: Predictive aspects of structural models. Reviewed
Casida, J. E.; Tomizawa, M.
Journal of Pesticide Science 33 4 - 8 2008.02
Authorship:Lead author Language:English Publishing type:Research paper (scientific journal)
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Atypical nicotinic agonist bound conformations conferring subtype selectivity. Reviewed
Tomizawa, M.; Maltby, D.; Talley, T. T.; Durkin, K. A.; Medzihradszky, K. F.; Burlingame, A. L.; Taylor, P; Casida, J. E.
Proceedings of the National Academy of Sciences of the United States of America 105 1728 - 1732 2008.02
Authorship:Lead author Language:English Publishing type:Research paper (scientific journal)
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Defining nicotinic agonist binding surfaces through photoaffinity labeling. Reviewed
Tomizawa, M.; Maltby, D.; Medzihradszky, K. F.; Zhang, N.; Durkin, K. A.; Presley, J.; Talley, T. T.; Taylor, P.; Burlingame, A. L.; Casida, J. E.
Biochemistry 46 8798 - 8806 2007.07
Authorship:Lead author Language:English Publishing type:Research paper (scientific journal)
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Mapping the elusive neonicotinoid binding site. Reviewed
Tomizawa, M.; Talley, T. T.; Maltby, D.; Durkin, K. A.; Medzihradszky, K. F.; Burlingame, A. L.; Taylor, P.; Casida, J. E.
Proceedings of the National Academy of Sciences of the United States of America 104 9075 - 9080 2007.05
Authorship:Lead author Language:English Publishing type:Research paper (scientific journal)
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Insect muscarinic receptor: pharmacological and toxicological profiles of antagonists and agonists. Reviewed
Honda, H.; Tomizawa, M.; Casida, J. E.
Journal of Agricultural and Food Chemistry 55 2276 - 2281 2007.03
Authorship:Corresponding author Language:English Publishing type:Research paper (scientific journal)
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Insect nicotinic acetylcholine receptors: neonicotinoid binding site specificity is usually but not always conserved with varied substituents and species. Reviewed
Honda, H.; Tomizawa, M.; Casida, J. E.
Journal of Agricultural and Food Chemistry 54 3365 - 3371 2006.05
Authorship:Corresponding author Language:English Publishing type:Research paper (scientific journal)
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Neonicotinoid metabolic activation and inactivation established with coupled nicotinic receptor-CYP3A4 and -aldehyde oxidase systems. Reviewed
Honda, H.; Tomizawa, M.; Casida, J. E.
Toxicology Letters 161 108 - 114 2006.02
Authorship:Corresponding author Language:English Publishing type:Research paper (scientific journal)
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Pharmacological profiles of recombinant and native insect nicotinic acetylcholine receptors. Reviewed
Tomizawa, M.; Millar, N. S.; Casida, J. E.
Insect Biochemistry and Molecular Biology 35 1347 - 1355 2005.12
Authorship:Lead author Language:English Publishing type:Research paper (scientific journal)
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Neonicotinoid nitroguanidine insecticide metabolites: synthesis and nicotinic receptor potency of guanidines, aminoguanidines, and their derivatives. Reviewed
Kanne, D. B.; Dick, R. A.; Tomizawa, M.; Casida, J. E.
Chemical Research in Toxicology 18 1479 - 1784 2005.09
Language:English Publishing type:Research paper (scientific journal)
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6’-Methylpyrido[3,4-b]- norhomotropane: synthesis and outstanding potency in relation to the alpha4beta2 nicotinic receptor pharmacophore model. Reviewed
Kanne, D. B.; Tomizawa, M.; Durkin, K. A.; Casida, J. E.
Bioorganic and Medicinal Chemistry Letters 15 877 - 881 2005.02
Language:English Publishing type:Research paper (scientific journal)
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Neonicotinoid insecticide toxicology: mechanisms of selective action. Reviewed
Tomizawa, M.; Casida, J. E.
Annual Review of Pharmacology and Toxicology 45 247 - 268 2005.01
Authorship:Lead author Language:English Publishing type:Research paper (scientific journal)
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Drosophila nicotinic receptors: evidence for imidacloprid insecticide and alpha-bungarotoxin binding to distinct sites. Reviewed
Zhang, N.; Tomizawa, M.; Casida, J. E.
Neuroscience Letters 371 56 - 59 2004.11
Authorship:Corresponding author Language:English Publishing type:Research paper (scientific journal)
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Neonicotinoids and derivatives: effects in mammalian cells and mice. Reviewed
Tomizawa, M.
Journal of Pesticide Science 29 177 - 183 2004.08
Language:English Publishing type:Research paper (scientific journal)